Interactor 1: CTR1 (P30825)
High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)
Gene: SLC7A1

Interactor 2: CTR2 (P52569)
Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2)
Gene: SLC7A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.712

The method score is based on:

Property Details
Experiments unassigned3799, unassigned3795
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains AA_permease_2~AA_permease_2
Common GO terms GO:0000064 - L-ornithine transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0006865 - amino acid transport
GO:0015171 - amino acid transmembrane transporter activity
GO:0015174 - basic amino acid transmembrane transporter activity
and 8 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 629
Hs

1 658
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ At
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025