Protein: OPRM
Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)

Gene: OPRM, OPRM1
Organism: Homo sapiens
Interactions: 140
UniProt ID: P35372

Gene Ontology (top 5):
GO:0001965 - G-protein alpha-subunit binding
GO:0004930 - G protein-coupled receptor activity
GO:0004979 - beta-endorphin receptor activity
GO:0005245 - voltage-gated calcium channel activity
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

723114

LPAR3
Lysophosphatidic acid receptor 3

2

14

High-throughput

0.783

High

723012

OPRD
Delta-type opioid receptor

2

14

Small-scale

0.754

High

537262

DRD2
D(2) dopamine receptor

1

18

Small-scale

0.724

High

723013

OPRX
Nociceptin receptor

1

14

Small-scale

0.724

High

723049

WLS
Protein wntless homolog

4

6

Small-scale

0.712

High

723091

RANB9
Ran-binding protein 9

2

4

Small-scale

0.654

High

716552

CXA4
Gap junction alpha-4 protein

2

5

Small-scale

0.651

High

723112

VAPA
Vesicle-associated membrane protein-associated protein A

2

7

Small-scale

0.651

High

199283

ZW10
Centromere/kinetochore protein zw10 homolog

2

2

High-throughput

0.628

High

723038

ATR
Serine/threonine-protein kinase ATR

2

13

High-throughput

0.628

High

723050

AB17B
Alpha/beta hydrolase domain-containing protein 17B

2

8

High-throughput

0.628

High

723051

ECM29
Proteasome adapter and scaffold protein ECM29

2

7

High-throughput

0.628

High

723053

LMBD2
G-protein coupled receptor-associated protein LMBRD2

2

9

High-throughput

0.628

High

723055

RINT1
RAD50-interacting protein 1

2

4

High-throughput

0.628

High

723078

COG1
Conserved oligomeric Golgi complex subunit 1

2

1

High-throughput

0.628

High

723088

COG3
Conserved oligomeric Golgi complex subunit 3

2

1

High-throughput

0.628

High

723090

XPO6
Exportin-6

2

2

High-throughput

0.628

High

450979

GNAO

1

17

Small-scale

0.618

High

596873

MAL
Myelin and lymphocyte protein

2

3

High-throughput

0.606

High

648006

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

1

High-throughput

0.606

High

723022

EMP1
Epithelial membrane protein 1

2

3

High-throughput

0.606

High

723023

EMP3
Epithelial membrane protein 3

2

3

High-throughput

0.606

High

723024

BI1
Bax inhibitor 1

2

4

High-throughput

0.606

High

723025

CLD8
Claudin-8

2

2

High-throughput

0.606

High

723027

CLD10
Claudin-10

2

2

High-throughput

0.606

High

723030

PMP22
Peripheral myelin protein 22

2

3

High-throughput

0.606

High

723034

SMAGP
Small cell adhesion glycoprotein

2

1

High-throughput

0.606

High

723035

MALL
MAL-like protein

2

3

High-throughput

0.606

High

723069

S41A1
Solute carrier family 41 member 1

2

1

High-throughput

0.606

High

723073

LRC25
Leucine-rich repeat-containing protein 25

2

1

High-throughput

0.606

High

723076

CLD22
Claudin-22

2

2

High-throughput

0.606

High

723093

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

8

High-throughput

0.606

High

723095

CLC7A
C-type lectin domain family 7 member A

2

3

High-throughput

0.606

High

723109

S38A7
Sodium-coupled neutral amino acid transporter 7

2

1

High-throughput

0.606

High

723016

HD
Huntingtin

2

0

High-throughput

0.602

High

723028

COG7
Conserved oligomeric Golgi complex subunit 7

2

0

High-throughput

0.602

High

723089

COG8
Conserved oligomeric Golgi complex subunit 8

2

0

High-throughput

0.602

High

723122

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

3

Small-scale

0.586

High

723045

Q4LE69
1-phosphatidylinositol 4-kinase

2

7

High-throughput

0.584

High

146954

C2C2L
Phospholipid transfer protein C2CD2L

2

0

High-throughput

0.580

High

207429

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.580

High

591183

AL5AP
Arachidonate 5-lipoxygenase-activating protein

2

0

High-throughput

0.580

High

723015

NSG1
Neuronal vesicle trafficking-associated protein 1

2

0

High-throughput

0.580

High

723031

IFM3
Interferon-induced transmembrane protein 3

2

0

High-throughput

0.580

High

723075

SERP2
Stress-associated endoplasmic reticulum protein 2

2

0

High-throughput

0.580

High

723123

TX264
Testis-expressed protein 264

2

0

High-throughput

0.580

High

176562

FANCA
Fanconi anemia group A protein

2

3

High-throughput

0.574

High

210638

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

2

2

High-throughput

0.574

High

297159

IPO13
Importin-13

2

12

High-throughput

0.574

High

335660

COX1
Cytochrome c oxidase subunit 1

2

1

High-throughput

0.574

High

723037

ATM
Serine-protein kinase ATM

2

14

High-throughput

0.574

High

723039

URB2
Unhealthy ribosome biogenesis protein 2 homolog

2

1

High-throughput

0.574

High

723040

COG2
Conserved oligomeric Golgi complex subunit 2

2

2

High-throughput

0.574

High

723046

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

2

9

High-throughput

0.574

High

723047

NOM1
Nucleolar MIF4G domain-containing protein 1

2

2

High-throughput

0.574

High

723054

ZFY26
Zinc finger FYVE domain-containing protein 26

2

2

High-throughput

0.574

High

723056

TTI2
TELO2-interacting protein 2

2

2

High-throughput

0.574

High

723057

MZT2B
Mitotic-spindle organizing protein 2B

2

4

High-throughput

0.574

High

723058

MBOA5
Lysophospholipid acyltransferase 5

2

7

High-throughput

0.574

High

723059

BRAT1
BRCA1-associated ATM activator 1

2

2

High-throughput

0.574

High

723060

THADA
tRNA

2

4

High-throughput

0.574

High

723063

MON2
Protein MON2 homolog

2

6

High-throughput

0.574

High

723064

ADCK1
AarF domain-containing protein kinase 1

2

6

High-throughput

0.574

High

723065

DAAF5
Dynein axonemal assembly factor 5

2

4

High-throughput

0.574

High

723072

INT1
Integrator complex subunit 1

2

5

High-throughput

0.574

High

723074

STAG2
Cohesin subunit SA-2

2

2

High-throughput

0.574

High

723083

GCP3
Gamma-tubulin complex component 3

2

9

High-throughput

0.574

High

723094

GCP2
Gamma-tubulin complex component 2

2

9

High-throughput

0.574

High

723099

XPO4
Exportin-4

2

14

High-throughput

0.574

High

723106

COG4
Conserved oligomeric Golgi complex subunit 4

2

2

High-throughput

0.574

High

723108

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

2

3

High-throughput

0.574

High

723115

MTFP1
Mitochondrial fission process protein 1

2

1

High-throughput

0.574

High

723118

GCP4
Gamma-tubulin complex component 4

2

9

High-throughput

0.574

High

723119

IPO11
Importin-11

2

13

High-throughput

0.574

High

723120

XPO7
Exportin-7

2

19

High-throughput

0.574

High

723116

DNJB4
DnaJ homolog subfamily B member 4

1

1

Small-scale

0.573

High

723043

CL12B
C-type lectin domain family 12 member B

2

3

High-throughput

0.553

High

723044

CTXN3
Cortexin-3

2

1

High-throughput

0.553

High

723087

SC22A
Vesicle-trafficking protein SEC22a

2

2

High-throughput

0.553

High

723096

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

2

4

High-throughput

0.553

High

723104

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

2

4

High-throughput

0.553

High

723107

RPRM
Protein reprimo

2

1

High-throughput

0.553

High

723014

PI4KA
Phosphatidylinositol 4-kinase alpha

2

8

High-throughput

0.552

High

723021

SC5A3
Sodium/myo-inositol cotransporter

2

3

High-throughput

0.552

High

723036

GRM1
Metabotropic glutamate receptor 1

1

6

High-throughput

0.541

High

723068

SL9A9
Sodium/hydrogen exchanger 9

1

3

High-throughput

0.541

High

723086

S39AD
Zinc transporter ZIP13

1

11

High-throughput

0.541

High

723100

YIPF3
Protein YIPF3

1

4

High-throughput

0.541

High

723102

KCNF1
Potassium voltage-gated channel subfamily F member 1

1

7

Small-scale

0.541

High

723117

ADDG
Gamma-adducin

1

3

High-throughput

0.541

High

168240

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

2

High-throughput

0.536

High

723062

DYM
Dymeclin

1

6

High-throughput

0.536

High

723079

CHPT1
Cholinephosphotransferase 1

1

4

High-throughput

0.536

High

723066

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

7

Small-scale

0.535

High

723077

DOK4
Docking protein 4

1

3

Small-scale

0.535

High

723081

CSN5
COP9 signalosome complex subunit 5

1

2

Small-scale

0.535

High

723103

NELFA
Negative elongation factor A

1

2

High-throughput

0.532

High

597983

FLNA
Filamin-A

1

5

Small-scale

0.529

High

723042

ZYX
Zyxin

1

0

Small-scale

0.529

High

199088

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

7

Small-scale

0.523

High

156107

CPLX1
Complexin-1

1

0

High-throughput

0.518

High

225294

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

1

0

High-throughput

0.518

High

475412

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

High-throughput

0.501

High

723084

RTP4
Receptor-transporting protein 4

1

2

High-throughput

0.494

High

213207

SNG2
Synaptogyrin-2

1

3

High-throughput

0.489

High

623207

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

4

High-throughput

0.489

High

723026

GEMI4
Gem-associated protein 4

1

1

High-throughput

0.489

High

723080

GCN1
Stalled ribosome sensor GCN1

1

10

High-throughput

0.489

High

723082

S2546
Mitochondrial outer membrane protein SLC25A46

1

2

High-throughput

0.489

High

723097

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.489

High

723121

TNPO3
Transportin-3

1

12

High-throughput

0.489

High

723071

TARG1
Trafficking regulator of GLUT4 1

1

6

High-throughput

0.481

High

159336

PLD2
Phospholipase D2

1

3

Small-scale

0.479

High

723029

ARF1
ADP-ribosylation factor 1

1

4

Small-scale

0.479

High

723092

SGMR1
Sigma non-opioid intracellular receptor 1

1

4

Small-scale

0.479

High

61015

A5PKU2
TUSC5 protein

1

6

High-throughput

0.470

High

723032

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.470

High

723033

Q08AM2
ADAM33 protein

1

2

High-throughput

0.470

High

723113

DOK5
Docking protein 5

1

3

Small-scale

0.464

High

351622

PENK
Proenkephalin-A [Cleaved into: Synenkephalin; Met-enkephalin

1

0

Small-scale

0.458

High

723048

GASP1
G-protein coupled receptor-associated sorting protein 1

1

6

Small-scale

0.457

High

723098

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

2

High-throughput

0.439

High

723110

TBA8
Tubulin alpha-8 chain

1

6

High-throughput

0.439

High

723041

TNIP1
TNFAIP3-interacting protein 1

1

2

Small-scale

0.437

High

130030

EXOC5
Exocyst complex component 5

2

0

High-throughput

0.328

High

723061

MMS22
Protein MMS22-like

2

0

High-throughput

0.328

High

723105

ZWILC
Protein zwilch homolog

2

0

High-throughput

0.328

High

175602

VA0E1
V-type proton ATPase subunit e 1

2

0

High-throughput

0.316

High

313588

CNIH1
Protein cornichon homolog 1

2

0

High-throughput

0.316

High

328111

SG1D1
Secretoglobin family 1D member 1

2

0

High-throughput

0.316

High

723017

T4S4
Transmembrane 4 L6 family member 4

2

0

High-throughput

0.316

High

723018

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

0

High-throughput

0.316

High

723020

CLCN7
H(+)/Cl(-) exchange transporter 7

2

0

High-throughput

0.316

High

723052

TM236
Transmembrane protein 236

2

0

High-throughput

0.316

High

723067

PLD3
5'-3' exonuclease PLD3

2

0

High-throughput

0.316

High

723070

CD302
CD302 antigen

2

0

High-throughput

0.316

High

723101

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

723111

CC167
Coiled-coil domain-containing protein 167

2

0

High-throughput

0.316

High

723085

TECT2
Tectonic-2

1

0

High-throughput

0.269

Low

723019

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024