HitPredict

Interactor 1: GDIA (P31150)
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Gene: GDI1

Interactor 2: RAB31 (Q13636)
Ras-related protein Rab-31 (EC 3.6.5.2) (Ras-related protein Rab-22B)
Gene: RAB31

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.900

Property	Details
Experiments	26496610, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 447 Hs			1 195
+	Hs
		631084 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5A_HUMAN (4-195): 2.86e-93: 272: 45.92
+	Hs
		724449 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5C_HUMAN (4-195): 1.28e-92: 270: 45.92
+	Hs
		724459 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB5B_HUMAN (2-195): 1.24e-91: 268: 44.44
+	Hs
		724529 GDIA_HUMAN (1-447): 0: 724: 100.00		RB22A_HUMAN (2-195): 7.06e-91: 265: 71.13
+	Hs
		724464 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1A_HUMAN (7-195): 2.43e-85: 251: 38.14
+	Hs
		724480 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11B_HUMAN (7-195): 6.26e-85: 251: 35.29
+	Hs
		724515 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1B_HUMAN (7-195): 1.84e-84: 249: 36.27
+	Mm
		894618 GDIA_MOUSE (1-447): 0: 722: 97.99		RAB1A_MOUSE (7-195): 2.43e-85: 251: 38.14
+	Hs
		631123 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5A_HUMAN (4-195): 2.86e-93: 272: 45.92
+	Hs
		894508 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5C_HUMAN (4-195): 1.28e-92: 270: 45.92
+	Hs
		894523 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB5B_HUMAN (2-195): 1.24e-91: 268: 44.44
+	Hs
		724460 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB10_HUMAN (7-195): 3.64e-81: 241: 38.22
+	Hs
		724463 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11A_HUMAN (7-195): 1.5e-80: 240: 35.15
+	Hs
		724498 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB2B_HUMAN (1-195): 1.71e-80: 240: 32.41
+	Hs
		724458 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB2A_HUMAN (1-186): 3.37e-80: 239: 36.84
+	Hs
		894530 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1A_HUMAN (7-195): 2.43e-85: 251: 38.14
+	Hs
		894524 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB10_HUMAN (7-195): 3.64e-81: 241: 38.22
+	Hs
		894529 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11A_HUMAN (7-195): 1.5e-80: 240: 35.15
+	Hs
		894522 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB2A_HUMAN (1-186): 3.37e-80: 239: 36.84
+	Hs
		894519 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB25_HUMAN (7-167): 5.53e-46: 152: 41.62