Interactor 1: HXC8 (P31273)
Homeobox protein Hox-C8 (Homeobox protein Hox-3A)
Gene: HOXC8

Interactor 2: HES6 (Q96HZ4)
Transcription cofactor HES-6 (C-HAIRY1) (Class B basic helix-loop-helix protein 41) (bHLHb41) (Hairy and enhancer of split 6)
Gene: HES6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~Homeodomain
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 242
Hs

1 224
+ Dm
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025