HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 323
+	Hs
		906551 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		PP1B_HUMAN (1-322): 0: 560: 86.89
+	Mm
		882679 FUS_MOUSE (1-526): 6.91e-34: 136: 86.72		PP1A_MOUSE (1-323): 0: 579: 90.36
+	Dm
		819258 CAZ_DROME (175-481): 5.46e-34: 134: 38.91		PP1B_DROME (1-323): 0: 552: 82.48
+	Hs
		737785 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Hs
		516386 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		PP1G_HUMAN (1-323): 0: 603: 100.00
+	Dm
		1099583 CAZ_DROME (175-481): 5.46e-34: 134: 38.91		Q8T0U6_DROME (19-323): 0: 535: 83.39
+	Hs
		905870 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Hs
		516441 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		PP1A_HUMAN (1-323): 0: 579: 90.66
+	Sp
		532280 PABP_SCHPO (242-381): 4.01e-12: 70.8: 15.71		PP11_SCHPO (7-322): 0: 555: 82.92
+	Zm
		6224 A0A1D6E6L1_MAIZE (280-380): 2.86e-10: 64.7: 19.80		B4FJL0_MAIZE (4-314): 0: 550: 75.24
+	Hs
		516454 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08