Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1
Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.763 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21343617, 19402821, 22337773, 21795849, 22307628, 37120454, 16603397, 15718470, 18566587, 21177249, 22990118, 25273559, 21339740, 17545609, 18566586, 16919458, 18411301, 35512704 |
| Identification Methods | pull down, enzymatic study, affinity chromatography technology, protein kinase assay, in-gel kinase assay |
| Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001938 - positive regulation of endothelial cell proliferation GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding and 3 others more... |
| Homologous interactions | 6 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
