HitPredict

Interactor 1: MYH11 (P35749)
Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Gene: MYH11

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	30561431, 36574265
Identification Methods	affinity chromatography technology, virotrap
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1972 Hs			1 636
+	Hs
		728528 MYH11_HUMAN (1-1972): 0: 1106: 100.00		SMC3_HUMAN (278-527): 2.28e-43: 169: 25.09
+	Hs
		148466 MYH11_HUMAN (1-1972): 0: 1106: 100.00		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		725097 MYH11_HUMAN (1-1972): 0: 1106: 100.00		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		724835 MYH9_HUMAN (885-1972): 1.2e-64: 246: 17.87		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		725164 MYH10_HUMAN (885-1971): 1.62e-63: 243: 19.36		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		1063911 MYH14_HUMAN (885-1970): 1.8e-56: 219: 17.79		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		148460 MYH9_HUMAN (885-1972): 1.2e-64: 246: 17.87		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		148461 MYH10_HUMAN (885-1971): 1.62e-63: 243: 19.36		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		724687 MYH9_HUMAN (885-1972): 1.2e-64: 246: 17.87		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		725095 MYH10_HUMAN (885-1971): 1.62e-63: 243: 19.36		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		724994 MYH9_HUMAN (885-1972): 1.2e-64: 246: 17.87		CP250_HUMAN (63-566): 3.97e-11: 68.8: 11.57
+	Hs
		522585 MYH7_HUMAN (1050-1972): 3.37e-57: 222: 17.60		MYH7_HUMAN (19-585): 1.55e-18: 92.7: 9.12
+	Hs
		522657 MYH7_HUMAN (1050-1972): 3.37e-57: 222: 17.60		MYH4_HUMAN (2-476): 3.89e-17: 88: 8.73
+	Hs
		724686 MYH9_HUMAN (885-1972): 1.2e-64: 246: 17.87		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		148991 MYH14_HUMAN (885-1970): 1.8e-56: 219: 17.79		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		1078856 MYH14_HUMAN (885-1970): 1.8e-56: 219: 17.79		ITSN1_HUMAN (92-469): 5.76e-14: 77.7: 11.00
+	Hs
		725189 MYH14_HUMAN (885-1970): 1.8e-56: 219: 17.79		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		724895 MYH14_HUMAN (885-1970): 1.8e-56: 219: 17.79		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33