HitPredict

Interactor 1: VGFR3 (P35916)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: FLT4

Interactor 2: LRC40 (Q9H9A6)
Leucine-rich repeat-containing protein 40
Gene: LRRC40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	I-set~LRR_8, LRR_8~ig, LRR_8~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1363 Hs			1 602
+	Hs
		665600 EPHB2_HUMAN (372-1320): 3.34e-154: 495: 12.87		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		1049958 EPHA7_HUMAN (392-1212): 1.3e-153: 492: 14.29		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		872473 EPHA5_HUMAN (373-1199): 1.28e-153: 493: 13.44		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		1072577 EPHA7_HUMAN (392-1212): 1.3e-153: 492: 14.29		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		665420 EPHA3_HUMAN (386-1200): 1.47e-152: 489: 14.15		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		738270 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		LRC40_HUMAN (1-256): 1.44e-25: 113: 21.45
+	Hs
		434266 RET_HUMAN (801-1176): 1.25e-74: 273: 40.63		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		557230 PGFRA_HUMAN (11-549): 8.68e-55: 211: 20.36		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		169176 MUSK_HUMAN (2-152): 6.12e-16: 85.4: 13.25		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		607966 FGFR4_HUMAN (535-810): 1.64e-14: 80.8: 15.79		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		507995 FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		169196 MUSK_HUMAN (2-152): 6.12e-16: 85.4: 13.25		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		169200 MUSK_HUMAN (2-152): 6.12e-16: 85.4: 13.25		LRRC1_HUMAN (41-220): 2.84e-14: 77.8: 31.11
+	Hs
		608091 FGFR4_HUMAN (535-810): 1.64e-14: 80.8: 15.79		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		508286 FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93		MFHA1_HUMAN (404-585): 1.78e-14: 79: 30.22
+	Mm
		1193423 PTK7_MOUSE (2-154): 5.42e-17: 89.3: 13.55		LRRC7_MOUSE (401-602): 7.57e-09: 60.8: 25.45
+	Hs
		601574 FGFR2_HUMAN (2-160): 1e-11: 71.9: 14.12		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61