Protein: IKBD
NF-kappa-B inhibitor delta (NFKB inhibitor delta) (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS) (T-cell activation NFKB-like protein) (TA-NFKBH)

Gene: IKBD, NFKBID
Organism: Homo sapiens
Interactions: 123
UniProt ID: Q8NI38

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006954 - inflammatory response
GO:0010468 - regulation of gene expression
GO:0050852 - T cell receptor signaling pathway
GO:2000321 - positive regulation of T-helper 17 cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

626294

NFKB1
Nuclear factor NF-kappa-B p105 subunit

2

20

High-throughput

0.811

High

1026748

NFKB2
Nuclear factor NF-kappa-B p100 subunit

2

18

High-throughput

0.811

High

1048925

REL
Proto-oncogene c-Rel

2

20

High-throughput

0.811

High

250294

VINEX
Vinexin

2

10

High-throughput

0.783

High

440147

LCK
Tyrosine-protein kinase Lck

2

13

High-throughput

0.783

High

681879

RBTN2
Rhombotin-2

2

7

High-throughput

0.783

High

1051394

ZBT16
Zinc finger and BTB domain-containing protein 16

2

2

High-throughput

0.783

High

1117968

PKP1
Plakophilin-1

2

10

High-throughput

0.783

High

1341208

LMO3
LIM domain only protein 3

2

7

High-throughput

0.783

High

1341242

LHX3
LIM/homeobox protein Lhx3

2

5

High-throughput

0.783

High

1341243

DDX25
ATP-dependent RNA helicase DDX25

2

9

High-throughput

0.783

High

1341223

SAM11
Sterile alpha motif domain-containing protein 11

2

0

High-throughput

0.742

High

1341234

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

0

High-throughput

0.742

High

222153

NCK2
Cytoplasmic protein NCK2

2

20

High-throughput

0.700

High

350485

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

18

High-throughput

0.700

High

965491

LMO4
LIM domain transcription factor LMO4

2

7

High-throughput

0.700

High

1341225

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

6

High-throughput

0.700

High

1341232

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

20

High-throughput

0.662

High

1341206

IKBD
NF-kappa-B inhibitor delta

1

18

High-throughput

0.621

High

1113762

CUL3
Cullin-3

1

20

High-throughput

0.618

High

292379

RA51D
DNA repair protein RAD51 homolog 4

2

2

High-throughput

0.606

High

352784

F107A
Actin-associated protein FAM107A

2

1

High-throughput

0.606

High

478705

HXB5
Homeobox protein Hox-B5

2

20

High-throughput

0.606

High

685272

PAX6
Paired box protein Pax-6

2

1

High-throughput

0.606

High

700468

PSB8
Proteasome subunit beta type-8

2

6

High-throughput

0.606

High

724916

HXD3
Homeobox protein Hox-D3

2

20

High-throughput

0.606

High

725094

HXC8
Homeobox protein Hox-C8

2

20

High-throughput

0.606

High

725151

HXC9
Homeobox protein Hox-C9

2

20

High-throughput

0.606

High

729359

HNRH1
Heterogeneous nuclear ribonucleoprotein H

2

11

High-throughput

0.606

High

885341

HXA1
Homeobox protein Hox-A1

2

20

High-throughput

0.606

High

899705

ANX11
Annexin A11

2

7

High-throughput

0.606

High

912972

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

11

High-throughput

0.606

High

940455

TCL1A
T-cell leukemia/lymphoma protein 1A

2

2

High-throughput

0.606

High

941023

HDAC4
Histone deacetylase 4

2

20

High-throughput

0.606

High

1031008

K22O
Keratin, type II cytoskeletal 2 oral

2

4

High-throughput

0.606

High

1055831

RING1
E3 ubiquitin-protein ligase RING1

2

12

High-throughput

0.606

High

1081412

INCA1
Protein INCA1

2

1

High-throughput

0.606

High

1086978

PO4F2
POU domain, class 4, transcription factor 2

2

2

High-throughput

0.606

High

1091234

FOXI1
Forkhead box protein I1

2

6

High-throughput

0.606

High

1106623

SMAD4
Mothers against decapentaplegic homolog 4

2

5

High-throughput

0.606

High

1156038

ZIC1
Zinc finger protein ZIC 1

2

6

High-throughput

0.606

High

1231237

NB5R2
NADH-cytochrome b5 reductase 2

2

3

High-throughput

0.606

High

1341210

CCHCR
Coiled-coil alpha-helical rod protein 1

2

4

High-throughput

0.606

High

1341212

TEKT4
Tektin-4

2

2

High-throughput

0.606

High

1341214

ESR2
Estrogen receptor beta

2

20

High-throughput

0.606

High

1341221

TEKT5
Tektin-5

2

2

High-throughput

0.606

High

1341224

RBM14
RNA-binding protein 14

2

4

High-throughput

0.606

High

1341235

DMRT3
Doublesex- and mab-3-related transcription factor 3

2

1

High-throughput

0.606

High

1341236

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

1

High-throughput

0.606

High

1341238

ANM7
Protein arginine N-methyltransferase 7

2

3

High-throughput

0.606

High

1341239

AIRIM
AFG2-interacting ribosome maturation factor

2

2

High-throughput

0.606

High

1341240

MYEF2
Myelin expression factor 2

2

13

High-throughput

0.606

High

1341244

IKZF3
Zinc finger protein Aiolos

2

2

High-throughput

0.606

High

1341215

XPF
DNA repair endonuclease XPF

2

0

High-throughput

0.602

High

91651

HSBPL
Heat shock factor-binding protein 1-like protein 1

2

0

High-throughput

0.580

High

335480

SLU7
Pre-mRNA-splicing factor SLU7

2

0

High-throughput

0.580

High

587147

ITF2
Transcription factor 4

2

0

High-throughput

0.580

High

871758

RFX2
DNA-binding protein RFX2

2

0

High-throughput

0.580

High

1007831

IRX6
Iroquois-class homeodomain protein IRX-6

2

0

High-throughput

0.580

High

1029878

RUNX1
Runt-related transcription factor 1

2

0

High-throughput

0.580

High

1341216

SNPC3
snRNA-activating protein complex subunit 3

2

0

High-throughput

0.580

High

1341230

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.580

High

1341231

BEX2
Protein BEX2

2

0

High-throughput

0.580

High

1341246

TCF19
Transcription factor 19

2

0

High-throughput

0.580

High

1149734

SSXT
Protein SSXT

2

3

High-throughput

0.576

High

1280033

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

7

High-throughput

0.555

High

164865

SH21B
SH2 domain-containing protein 1B

2

14

High-throughput

0.553

High

281377

GGYF1
GRB10-interacting GYF protein 1

2

6

High-throughput

0.553

High

300435

KRT34
Keratin, type I cuticular Ha4

2

4

High-throughput

0.553

High

334445

SYFM
Phenylalanine--tRNA ligase, mitochondrial

2

3

High-throughput

0.553

High

341815

K2C75
Keratin, type II cytoskeletal 75

2

4

High-throughput

0.553

High

474842

VIME
Vimentin

2

15

High-throughput

0.553

High

475639

K1C19
Keratin, type I cytoskeletal 19

2

4

High-throughput

0.553

High

570513

GFAP
Glial fibrillary acidic protein

2

16

High-throughput

0.553

High

868215

SYQ
Glutamine--tRNA ligase

2

2

High-throughput

0.553

High

922364

CRBA2
Beta-crystallin A2

2

1

High-throughput

0.553

High

1090805

TRAF2
TNF receptor-associated factor 2

2

17

High-throughput

0.553

High

1102349

GRB10
Growth factor receptor-bound protein 10

2

17

High-throughput

0.553

High

1120934

TRI29
Tripartite motif-containing protein 29

2

13

High-throughput

0.553

High

1124380

ELOA1
Elongin-A

2

11

High-throughput

0.553

High

1135984

RTP5
Receptor-transporting protein 5

2

2

High-throughput

0.553

High

1276134

NUP54
Nucleoporin p54

2

1

High-throughput

0.553

High

1287099

PATL1
Protein PAT1 homolog 1

2

7

High-throughput

0.553

High

1330506

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

2

9

High-throughput

0.553

High

1331899

DTX3
Probable E3 ubiquitin-protein ligase DTX3

2

1

High-throughput

0.553

High

1341207

G45IP
Large ribosomal subunit protein mL64

2

1

High-throughput

0.553

High

1341209

PPL13
Placental protein 13-like

2

1

High-throughput

0.553

High

1341217

ARHG2
Rho guanine nucleotide exchange factor 2

2

12

High-throughput

0.553

High

1341219

RBM41
RNA-binding protein 41

2

8

High-throughput

0.553

High

1341226

CTRC
Chymotrypsin-C

2

2

High-throughput

0.553

High

1341227

RBM4B
RNA-binding protein 4B

2

9

High-throughput

0.553

High

1341228

UTP23
rRNA-processing protein UTP23 homolog

2

2

High-throughput

0.553

High

1341241

TFP11
Tuftelin-interacting protein 11

2

1

High-throughput

0.553

High

1341245

SMAG1
Protein Smaug homolog 1

2

1

High-throughput

0.553

High

1341213

RSPH1
Radial spoke head 1 homolog

1

2

High-throughput

0.541

High

1230153

K1C40
Keratin, type I cytoskeletal 40

1

4

High-throughput

0.523

High

1232477

Q6FHY5
MEOX2 protein

1

20

High-throughput

0.515

High

786181

LONM
Lon protease homolog, mitochondrial

1

12

High-throughput

0.489

High

894040

MEOX2
Homeobox protein MOX-2

1

20

High-throughput

0.481

High

116957

J3KNH0
KICSTOR subunit 2

1

1

High-throughput

0.470

High

1196854

Q4VAX2
Synovial sarcoma translocation, chromosome 18

1

5

High-throughput

0.470

High

1341211

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

3

High-throughput

0.439

High

1341222

KICS2
KICSTOR subunit 2

1

1

High-throughput

0.439

High

1241224

CA094
Uncharacterized protein C1orf94

4

0

High-throughput

0.364

High

271076

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

2

0

High-throughput

0.316

High

377067

COLI
Pro-opiomelanocortin

2

0

High-throughput

0.316

High

605474

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.316

High

1094063

RM28
Large ribosomal subunit protein bL28m

2

0

High-throughput

0.316

High

1186668

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

1193121

PKHN1
Pleckstrin homology domain-containing family N member 1

2

0

High-throughput

0.316

High

1206406

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1216354

ZC21B
Zinc finger C2HC domain-containing protein 1B

2

0

High-throughput

0.316

High

1239772

FAP20
Fanconi anemia core complex-associated protein 20

2

0

High-throughput

0.316

High

1250263

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

1280119

SEN54
tRNA-splicing endonuclease subunit Sen54

2

0

High-throughput

0.316

High

1309103

GLCTK
Glycerate kinase

2

0

High-throughput

0.316

High

1314592

IHO1
Interactor of HORMAD1 protein 1

2

0

High-throughput

0.316

High

1341218

RM53
Large ribosomal subunit protein mL53

2

0

High-throughput

0.316

High

1341220

SMIP2
Protein SPMIP2

2

0

High-throughput

0.316

High

1341229

NICN1
Nicolin-1

2

0

High-throughput

0.316

High

1341233

SMG9
Nonsense-mediated mRNA decay factor SMG9

2

0

High-throughput

0.316

High

1341237

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025