HitPredict

Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0043066 - negative regulation of apoptotic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1356 Hs			1 4128
+	Hs
		452388 PGFRB_HUMAN (33-555): 3.92e-53: 205: 18.45		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		601494 FGFR2_HUMAN (1-231): 3.47e-24: 112: 9.57		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		572617 VGFR1_HUMAN (1-131): 5.1e-20: 99.3: 13.38		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		738194 FLT3_HUMAN (40-555): 7.17e-20: 98.5: 16.22		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		609246 FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		729260 VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		738299 FLT3_HUMAN (40-555): 7.17e-20: 98.5: 16.22		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		452416 PGFRB_HUMAN (33-555): 3.92e-53: 205: 18.45		ATR_HUMAN (3377-4128): 2.05e-122: 438: 19.28