HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: TENS2 (Q63HR2)
Tensin-2 (EC 3.1.3.48) (C1 domain-containing phosphatase and tensin homolog) (C1-TEN) (Tensin-like C1 domain-containing phosphatase)
Gene: TNS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1409
+	Hs
		971632 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		TENS2_HUMAN (1-1409): 0: 746: 100.00
+	Hs
		729931 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		TENS2_HUMAN (1-1409): 0: 746: 100.00
+	Hs
		1049405 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		TENS2_HUMAN (1-1409): 0: 746: 100.00
+	Hs
		691117 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		TENS3_HUMAN (125-1409): 1.59e-168: 545: 33.49
+	Hs
		729933 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		TENS3_HUMAN (125-1409): 1.59e-168: 545: 33.49
+	Hs
		730665 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		TENS3_HUMAN (125-1409): 1.59e-168: 545: 33.49
+	Hs
		1049410 1433F_HUMAN (2-242): 7.19e-106: 307: 71.43		TENS3_HUMAN (125-1409): 1.59e-168: 545: 33.49
+	Mm
		147750 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		PTEN_MOUSE (118-478): 1.23e-114: 367: 24.37
+	Dm
		709541 1433Z_DROME (1-245): 3.69e-141: 397: 77.14		Q7KMQ6_DROME (107-528): 1.03e-98: 328: 19.74
+	Hs
		319058 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		K0754_HUMAN (951-1399): 2.89e-25: 116: 9.47
+	Hs
		319061 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		K0754_HUMAN (951-1399): 2.89e-25: 116: 9.47
+	Hs
		319052 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		K0754_HUMAN (951-1399): 2.89e-25: 116: 9.47
+	Hs
		971678 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		OTOG_HUMAN (412-933): 1.29e-15: 85.1: 11.68
+	Hs
		730756 1433S_HUMAN (1-236): 9.9e-108: 312: 71.85		TENS4_HUMAN (847-1409): 5.04e-44: 174: 32.50
+	Hs
		691153 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		OTOG_HUMAN (412-933): 1.29e-15: 85.1: 11.68
+	Hs
		990385 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		OTOG_HUMAN (412-933): 1.29e-15: 85.1: 11.68
+	Hs
		729976 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		OTOG_HUMAN (412-933): 1.29e-15: 85.1: 11.68
+	Hs
		691449 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		TENS1_HUMAN (414-1346): 1.6e-12: 74.8: 11.54
+	Hs
		990757 1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59		TENS1_HUMAN (414-1346): 1.6e-12: 74.8: 11.54
+	Hs
		730259 1433B_HUMAN (1-242): 5.04e-139: 391: 81.82		TENS1_HUMAN (414-1346): 1.6e-12: 74.8: 11.54