HitPredict

Interactor 1: CENPA (P36012)
Histone H3-like centromeric protein CSE4 (CENP-A homolog) (CENPA homolog) (Chromosome segregation protein 4)
Gene: CSE4

Interactor 2: VPS75 (P53853)
Vacuolar protein sorting-associated protein 75
Gene: VPS75

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21070971
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Sc			1 264
+	Hs
		1086346 H31T_HUMAN (93-227): 1.42e-51: 165: 48.91		TSYL4_HUMAN (16-235): 3.23e-69: 220: 15.32
+	Sc
		865358 H3_YEAST (93-227): 4.85e-44: 146: 47.45		VPS75_YEAST (1-264): 1.43e-77: 237: 100.00
+	Hs
		934935 H31_HUMAN (93-227): 9.76e-53: 168: 51.10		TSYL5_HUMAN (16-231): 2.59e-58: 192: 19.09
+	Hs
		934666 H31_HUMAN (93-227): 9.76e-53: 168: 51.10		SET_HUMAN (6-216): 4.04e-59: 191: 18.27
+	Hs
		952444 H33_HUMAN (93-227): 3.02e-51: 164: 51.83		TSYL5_HUMAN (16-231): 2.59e-58: 192: 19.09
+	Hs
		963827 H31T_HUMAN (93-227): 1.42e-51: 165: 48.91		SET_HUMAN (6-216): 4.04e-59: 191: 18.27
+	At
		886475 H33_ARATH (93-227): 1.56e-52: 167: 51.10		NAP1B_ARATH (5-221): 6.95e-57: 188: 15.04
+	Hs
		952277 H33_HUMAN (93-227): 3.02e-51: 164: 51.83		SET_HUMAN (6-216): 4.04e-59: 191: 18.27
+	Hs
		963844 H32_HUMAN (93-227): 3.71e-51: 164: 51.83		SET_HUMAN (6-216): 4.04e-59: 191: 18.27
+	At
		886672 H31_ARATH (93-227): 2.92e-51: 164: 50.37		NAP1B_ARATH (5-221): 6.95e-57: 188: 15.04
+	At
		886474 H33_ARATH (93-227): 1.56e-52: 167: 51.10		NAP1A_ARATH (5-222): 1.1e-54: 182: 13.06
+	Hs
		876755 H31_HUMAN (93-227): 9.76e-53: 168: 51.10		NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78
+	Hs
		1086291 H31T_HUMAN (93-227): 1.42e-51: 165: 48.91		NP1L4_HUMAN (5-225): 1.39e-54: 181: 13.95
+	At
		886466 H33_ARATH (93-227): 1.56e-52: 167: 51.10		NAP1C_ARATH (5-223): 7.42e-54: 179: 12.69
+	At
		886671 H31_ARATH (93-227): 2.92e-51: 164: 50.37		NAP1A_ARATH (5-222): 1.1e-54: 182: 13.06
+	Hs
		1174639 H32_HUMAN (93-227): 3.71e-51: 164: 51.83		NP1L4_HUMAN (5-225): 1.39e-54: 181: 13.95
+	Hs
		876827 H32_HUMAN (93-227): 3.71e-51: 164: 51.83		NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78
+	At
		886665 H31_ARATH (93-227): 2.92e-51: 164: 50.37		NAP1C_ARATH (5-223): 7.42e-54: 179: 12.69
+	Dm
		356123 H3_DROME (93-227): 3.71e-51: 164: 51.83		Q9W1G7_DROME (20-263): 1.69e-49: 168: 14.98
+	Sp
		1336870 CENPA_SCHPO (118-226): 3.38e-44: 146: 56.25		YO48_SCHPO (10-219): 1.42e-39: 139: 27.65