HitPredict

Interactor 1: SN114 (P36048)
Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10)
Gene: SNU114

Interactor 2: CWC2 (Q12046)
Pre-mRNA-splicing factor CWC2 (Complexed with CEF1 protein 2) (PRP19-associated complex protein 40) (Synthetic lethal with CLF1 protein 3)
Gene: CWC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	11884590, 16429126, 37968396, 14690591
Identification Methods	affinity chromatography technology, tandem affinity purification, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0000398 - mRNA splicing, via spliceosome GO:0071007 - U2-type catalytic step 2 spliceosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1008 Sc			1 339
+	Hs
		1064773 U5S1_HUMAN (2-1007): 0: 898: 31.43		RBM22_HUMAN (5-253): 3.12e-81: 254: 20.93
+	Sp
		292942 SN114_SCHPO (1-1007): 0: 841: 32.82		CWC2_SCHPO (7-302): 1.19e-76: 242: 35.64
+	Sc
		731755 SN114_YEAST (1-1008): 0: 895: 100.00		NAM8_YEAST (6-233): 3.5e-25: 107: 15.16
+	Hs
		165484 U5S1_HUMAN (2-1007): 0: 898: 31.43		SR140_HUMAN (123-296): 1.8e-12: 70.3: 18.56