HitPredict

Interactor 1: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Interactor 2: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 993 Hs			1 2671
+	Hs
		572666 VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31		GCN1_HUMAN (1-2671): 0: 2129: 100.00
+	Hs
		729326 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		GCN1_HUMAN (1-2671): 0: 2129: 100.00
+	Hs
		127200 FLT3_HUMAN (1-993): 0: 844: 97.89		IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18
+	Hs
		738225 FLT3_HUMAN (1-993): 0: 844: 97.89		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		127198 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18
+	Hs
		507873 FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90		2AAB_HUMAN (2265-2670): 2.67e-36: 149: 14.67
+	Hs
		127184 FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09		IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18
+	Hs
		609345 FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24