Interactor 1: FGF7 (P21781)
Fibroblast growth factor 7 (FGF-7) (Heparin-binding growth factor 7) (HBGF-7) (Keratinocyte growth factor)
Gene: FGF7

Interactor 2: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 10702276
Identification Methods pull down, affinity chromatography technology, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FGF~I-set, FGF~Ig_3
Common GO terms GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0030154 - cell differentiation
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 194
Hs

1 4391
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024