HitPredict

Interactor 1: ISW1 (P38144)
ISWI chromatin-remodeling complex ATPase ISW1 (EC 3.6.4.-)
Gene: ISW1

Interactor 2: NHP10 (Q03435)
Non-histone protein 10 (High mobility group protein 2)
Gene: NHP10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1129 Sc			1 203
+	Sc
		514173 ISW1_YEAST (1-1129): 0: 932: 100.00		NHP6A_YEAST (78-162): 3.8e-25: 95.6: 31.46
+	Sc
		514251 ISW1_YEAST (1-1129): 0: 932: 100.00		NHP6B_YEAST (78-162): 4.26e-25: 95.6: 32.58
+	Sc
		976405 ISW2_YEAST (19-1108): 0: 803: 46.97		NHP10_YEAST (1-203): 5.56e-62: 193: 100.00
+	Mm
		1142014 SMCA5_MOUSE (86-1094): 0: 874: 46.69		Q60I23_MOUSE (62-178): 5.5e-29: 111: 14.88
+	Hs
		229467 SMCA5_HUMAN (86-1094): 0: 869: 46.69		CIC_HUMAN (44-201): 6.64e-29: 114: 16.76
+	Hs
		229339 SMCA5_HUMAN (86-1094): 0: 869: 46.69		SOX2_HUMAN (63-178): 1.49e-29: 112: 15.00
+	Hs
		229376 SMCA5_HUMAN (86-1094): 0: 869: 46.69		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85
+	Hs
		658657 SMCA1_HUMAN (70-1079): 0: 869: 46.98		SSRP1_HUMAN (72-186): 2.34e-26: 107: 21.85
+	Hs
		229284 SMCA5_HUMAN (86-1094): 0: 869: 46.69		HMGB1_HUMAN (80-160): 1.31e-19: 84.5: 31.77
+	Hs
		449557 SMCA1_HUMAN (70-1079): 0: 869: 46.98		HMGB1_HUMAN (80-160): 1.31e-19: 84.5: 31.77
+	Zm
		9144 A0A1D6FIP6_MAIZE (70-1115): 0: 836: 43.10		A0A1D6EUM9_MAIZE (83-192): 4.32e-28: 105: 20.00
+	Mm
		57186 CHD7_MOUSE (25-1127): 0: 808: 26.50		Q60I23_MOUSE (62-178): 5.5e-29: 111: 14.88
+	Hs
		1300971 CHD7_HUMAN (25-1127): 0: 804: 26.50		CIC_HUMAN (44-201): 6.64e-29: 114: 16.76
+	Hs
		818550 CHD7_HUMAN (25-1127): 0: 804: 26.50		SOX2_HUMAN (63-178): 1.49e-29: 112: 15.00
+	Hs
		818841 CHD7_HUMAN (25-1127): 0: 804: 26.50		SOX9_HUMAN (44-202): 6.4e-28: 111: 17.16
+	Hs
		881831 CHD7_HUMAN (25-1127): 0: 804: 26.50		SOX10_HUMAN (37-194): 2.56e-27: 109: 16.77
+	Hs
		1332326 CHD7_HUMAN (25-1127): 0: 804: 26.50		SOX17_HUMAN (63-197): 2.66e-27: 108: 14.39
+	Sc
		514218 ISW2_YEAST (19-1108): 0: 803: 46.97		NHP6A_YEAST (78-162): 3.8e-25: 95.6: 31.46
+	Sc
		514275 ISW2_YEAST (19-1108): 0: 803: 46.97		NHP6B_YEAST (78-162): 4.26e-25: 95.6: 32.58
+	Hs
		225761 CHD5_HUMAN (45-1127): 0: 782: 25.58		SOX15_HUMAN (62-174): 3.51e-26: 102: 16.10