HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16159877
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 2752
+	Hs
		1357564 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1020354 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		516749 PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		745272 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		516546 PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		745090 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		1289243 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22
+	Hs
		1031405 PABP4_HUMAN (9-98): 1.43e-19: 92.6: 28.89		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		516609 PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		958223 RBM3_HUMAN (8-88): 3.03e-15: 74.3: 55.56		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		820908 PABP4_HUMAN (9-98): 1.43e-19: 92.6: 28.89		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		820889 TIAR_HUMAN (1-344): 2.52e-18: 87.6: 15.23		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		516406 PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		516766 PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		516595 PABP1_HUMAN (6-93): 1.47e-17: 86.4: 27.27		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		965152 PABP3_HUMAN (6-93): 1.58e-15: 80.3: 23.86		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23