Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Interactor 2: UIMC1 (Q96RL1)
BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1)
Gene: UIMC1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.764 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25252691, 28569838, 17525341, 19615732, 21622030, 19261748, 17621610, 17525340, 25184681, 29656893, 26027929, 34408138, 17525342, 34591612, 19305427, 24085845, 17643121 |
| Identification Methods | affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006282 - regulation of DNA repair GO:0006302 - double-strand break repair and 7 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
