Interactor 1: PRS6A (P33297)
26S proteasome regulatory subunit 6A (Tat-binding protein homolog 1) (TBP-1)
Gene: RPT5

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 15117943, 16554755, 18467557, 15687504, 36621624, 23900548, 37968396, 16284124, 31848235
Identification Methods affinity chromatography technology, protein complementation assay, two hybrid, cross-linking study, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB_C~Prot_ATP_ID_OB_C
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0016887 - ATP hydrolysis activity
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 434
Sc

1 405
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Af
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025