HitPredict

Interactor 1: SEC3 (P33332)
Exocyst complex component SEC3 (Protein PSL1)
Gene: SEC3

Interactor 2: TEM1 (P38987)
Protein TEM1
Gene: TEM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	33481703
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Sec3-PIP2_bind
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1336 Sc			1 245
+	Sc
		458552 SEC3_YEAST (1-1336): 0: 1227: 100.00		SEC4_YEAST (21-185): 9.46e-16: 75.1: 27.71
+	Hs
		1145193 MYO5A_HUMAN (233-778): 1.4e-33: 143: 14.41		RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14
+	Hs
		157111 CTRO_HUMAN (60-746): 2.72e-30: 132: 9.00		RAB13_HUMAN (13-212): 3.15e-88: 261: 20.90
+	Hs
		1145196 MRCKB_HUMAN (175-717): 5.46e-26: 118: 9.89		RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14
+	Hs
		157196 CTRO_HUMAN (60-746): 2.72e-30: 132: 9.00		RAB1A_HUMAN (10-217): 5.45e-83: 248: 21.05
+	Hs
		976691 MYO5A_HUMAN (233-778): 1.4e-33: 143: 14.41		RB11A_HUMAN (10-227): 7e-78: 235: 18.72
+	Hs
		157837 CTRO_HUMAN (60-746): 2.72e-30: 132: 9.00		RAB1B_HUMAN (13-215): 2.39e-80: 241: 21.57
+	Dm
		197104 TGO1_DROME (262-466): 1.66e-27: 123: 24.34		O18332_DROME (10-217): 9.16e-80: 240: 22.01
+	Hs
		270793 ROCK2_HUMAN (282-936): 2.18e-25: 116: 11.51		RB11A_HUMAN (10-227): 7e-78: 235: 18.72
+	Hs
		1144949 MRCKA_HUMAN (591-879): 4.34e-15: 83.3: 10.81		RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14
+	Hs
		1144919 ITSN1_HUMAN (616-917): 7.14e-11: 69.4: 9.43		RAB35_HUMAN (13-212): 1.76e-88: 262: 24.14
+	Hs
		976324 MRCKA_HUMAN (591-879): 4.34e-15: 83.3: 10.81		RB11A_HUMAN (10-227): 7e-78: 235: 18.72
+	Hs
		976290 ITSN1_HUMAN (616-917): 7.14e-11: 69.4: 9.43		RB11A_HUMAN (10-227): 7e-78: 235: 18.72
+	Hs
		901298 MRCKA_HUMAN (591-879): 4.34e-15: 83.3: 10.81		RAB7A_HUMAN (16-207): 1.17e-15: 74.7: 26.40