HitPredict

Interactor 1: GCYA2 (P33402)
Guanylate cyclase soluble subunit alpha-2 (GCS-alpha-2) (EC 4.6.1.2)
Gene: GUCY1A2

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.567

Property	Details
Experiments	24550280, 30126976
Identification Methods	affinity chromatography technology, phage display, anti tag coimmunoprecipitation, p8 filamentous phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1655
+	Rn
		723906 GCYA2_RAT (1-732): 0: 907: 90.98		DLG4_RAT (812-1187): 5.61e-49: 189: 22.42
+	Hs
		752038 GCYA2_HUMAN (1-732): 0: 865: 100.00		DLG4_HUMAN (812-1187): 5.87e-49: 189: 22.42
+	Rn
		1224266 GCYA2_RAT (1-732): 0: 907: 90.98		DLG1_RAT (955-1182): 3.1e-24: 112: 37.56
+	Rn
		1224611 GCYA2_RAT (1-732): 0: 907: 90.98		DLG2_RAT (816-1021): 6.73e-21: 101: 22.33
+	Rn
		1224330 GCYA2_RAT (1-732): 0: 907: 90.98		DLG3_RAT (724-947): 3.66e-19: 96.3: 31.23
+	Hs
		752045 GCYA2_HUMAN (1-732): 0: 865: 100.00		DLG3_HUMAN (724-947): 1.79e-19: 97.4: 31.23
+	Hs
		752044 GCYA2_HUMAN (1-732): 0: 865: 100.00		DLG2_HUMAN (591-851): 2.07e-16: 87.5: 16.79
+	Hs
		752040 GCYA2_HUMAN (1-732): 0: 865: 100.00		DLG1_HUMAN (687-910): 5.8e-15: 82.9: 24.68
+	Hs
		752046 GCYA2_HUMAN (1-732): 0: 865: 100.00		ERBIN_HUMAN (541-949): 3.85e-10: 67.1: 13.27
+	Rn
		633436 GCYB1_RAT (112-705): 0: 646: 33.76		DLG4_RAT (812-1187): 5.61e-49: 189: 22.42