Interactor 1: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Interactor 2: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 37968396, 22940862, 9584156, 16554755, 16429126, 19446323, 22237024, 14759368
Identification Methods affinity chromatography technology, biochemical, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0030234 - enzyme regulator activity
GO:0042176 - regulation of protein catabolic process
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 993
Sc

1 523
+ Hs
+ At
+ Sp
+ Dm
+ Hs
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024