HitPredict

Interactor 1: NADE (P38795)
Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing])
Gene: QNS1

Interactor 2: NADE (P38795)
Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing])
Gene: QNS1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.889

Property	Details
Experiments	11283351, 18467557, 18719252, 22615397
Identification Methods	two hybrid, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CN_hydrolase~CN_hydrolase, CN_hydrolase~NAD_synthase, NAD_synthase~NAD_synthase
Common GO terms	GO:0003952 - NAD+ synthase (glutamine-hydrolyzing) activity GO:0004359 - glutaminase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 1 others more... GO:0009435 - NAD biosynthetic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 714 Sc			1 714
+	Sp
		252337 NADE_SCHPO (1-704): 0: 1028: 60.23		NADE_SCHPO (1-704): 0: 1028: 60.23
+	At
		1320057 NADE_ARATH (3-700): 0: 999: 54.30		NADE_ARATH (3-700): 0: 999: 54.30
+	Mt
		958623 NADE_MYCTU (4-631): 2.68e-172: 511: 23.48		NADE_MYCTU (4-631): 2.68e-172: 511: 23.48
+	Ec
		578880 NADE_ECOLI (333-607): 1.78e-52: 184: 17.75		NADE_ECOLI (333-607): 1.78e-52: 184: 17.75
+	Cj
		1351500 NADE_CAMJE (334-605): 2.11e-52: 183: 19.85		NADE_CAMJE (334-605): 2.11e-52: 183: 19.85