HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: RN167 (Q9H6Y7)
E3 ubiquitin-protein ligase RNF167 (EC 2.3.2.27) (RING finger protein 167)
Gene: RNF167

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 350
+	Hs
		957671 UBE2K_HUMAN (1-97): 6.08e-34: 117: 100.00		RN167_HUMAN (1-333): 2.77e-91: 278: 100.00
+	Hs
		982322 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RN167_HUMAN (1-333): 2.77e-91: 278: 100.00
+	Hs
		957200 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		RN167_HUMAN (1-333): 2.77e-91: 278: 100.00
+	Hs
		220490 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RNF13_HUMAN (17-347): 3.91e-77: 243: 47.43
+	Hs
		220488 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		RNF13_HUMAN (17-347): 3.91e-77: 243: 47.43
+	Hs
		982363 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RN150_HUMAN (40-342): 4.41e-57: 193: 24.31
+	Hs
		957145 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		RN128_HUMAN (17-341): 9.8e-58: 194: 20.56
+	Hs
		982262 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		ZNRF4_HUMAN (8-346): 7.28e-57: 192: 33.43
+	Hs
		957147 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		ZNRF4_HUMAN (8-346): 7.28e-57: 192: 33.43
+	Hs
		982249 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RN149_HUMAN (33-305): 6.62e-56: 189: 21.14
+	Hs
		957135 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		RN149_HUMAN (33-305): 6.62e-56: 189: 21.14
+	Hs
		982231 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		GOLI_HUMAN (43-345): 5.24e-53: 182: 21.41
+	Hs
		957124 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		GOLI_HUMAN (43-345): 5.24e-53: 182: 21.41
+	Hs
		982211 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RNF43_HUMAN (40-346): 1.14e-43: 162: 21.08
+	Hs
		957101 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		RNF43_HUMAN (40-346): 1.14e-43: 162: 21.08
+	Hs
		957679 UBE2K_HUMAN (1-97): 6.08e-34: 117: 100.00		RNF12_HUMAN (175-278): 2.81e-28: 117: 32.69
+	Hs
		982337 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RNF12_HUMAN (175-278): 2.81e-28: 117: 32.69
+	Hs
		982225 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		SYVN1_HUMAN (104-294): 7.04e-27: 113: 17.35
+	Hs
		957118 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		SYVN1_HUMAN (104-294): 7.04e-27: 113: 17.35
+	Hs
		982325 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RN122_HUMAN (168-275): 4.84e-27: 106: 29.09