HitPredict

Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: HDAC7 (Q8WUI4)
Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) (Protein deacetylase HDAC7) (EC 3.5.1.-)
Gene: HDAC7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

Property	Details
Experiments	26496610, 36931259, 33961781, 20224040, 23752268, 17979178, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 952
+	Hs
		909856 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC7_HUMAN (1-952): 0: 1051: 100.00
+	Hs
		904911 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		HDAC7_HUMAN (1-952): 0: 1051: 100.00
+	Mm
		910299 1433E_MOUSE (1-244): 1.37e-141: 398: 62.71		HDAC7_MOUSE (1-952): 0: 986: 85.42
+	Hs
		880661 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC4_HUMAN (20-939): 0: 958: 48.44
+	Hs
		880659 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		HDAC4_HUMAN (20-939): 0: 958: 48.44
+	Hs
		880691 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		HDAC4_HUMAN (20-939): 0: 958: 48.44
+	Hs
		880673 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		HDAC4_HUMAN (20-939): 0: 958: 48.44
+	Hs
		910144 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC9_HUMAN (20-892): 0: 869: 43.28
+	Mm
		910239 1433E_MOUSE (1-244): 1.37e-141: 398: 62.71		Q3UJF1_MOUSE (20-950): 0: 851: 41.88
+	Hs
		910173 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC5_HUMAN (20-950): 0: 850: 41.21
+	Mm
		910352 1433E_MOUSE (1-244): 1.37e-141: 398: 62.71		HDAC5_MOUSE (20-950): 0: 842: 41.49
+	Hs
		905272 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		HDAC5_HUMAN (20-950): 0: 850: 41.21
+	Mm
		935495 1433F_MOUSE (1-246): 6.15e-136: 383: 99.19		Q3UJF1_MOUSE (20-950): 0: 851: 41.88
+	Hs
		982633 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		HDAC5_HUMAN (20-950): 0: 850: 41.21
+	Mm
		935719 1433F_MOUSE (1-246): 6.15e-136: 383: 99.19		HDAC5_MOUSE (20-950): 0: 842: 41.49
+	Hs
		909530 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC1_HUMAN (510-916): 1.27e-170: 507: 21.91
+	Hs
		177251 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC3_HUMAN (518-951): 2.59e-161: 481: 20.00
+	Hs
		910121 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC6_HUMAN (443-951): 2.96e-115: 383: 30.33
+	Dm
		664668 1433Z_DROME (3-242): 8.23e-108: 312: 73.33		Q9VYF3_DROME (50-490): 2.74e-68: 250: 20.08
+	Dm
		664611 1433Z_DROME (3-242): 8.23e-108: 312: 73.33		Q59E49_DROME (50-490): 9.5e-58: 218: 18.40