HitPredict

Interactor 1: SFB3 (P38810)
SED5-binding protein 3 (Lethal with SEC13 protein 1) (SEC24-related protein 3)
Gene: SFB3

Interactor 2: SEC24 (P40482)
Protein transport protein SEC24 (Abnormal nuclear morphology 1)
Gene: SEC24

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 23904270, 18467557
Identification Methods affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Gelsolin~Gelsolin, Gelsolin~Sec23_helical, Gelsolin~Sec23_trunk, Sec23_BS~Sec23_helical, Sec23_BS~Sec23_trunk, Sec23_BS~zf-Sec23_Sec24, Sec23_helical~Sec23_trunk, Sec23_trunk~Sec23_trunk, zf-Sec23_Sec24~zf-Sec23_Sec24
Common GO terms GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0005048 - signal sequence binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
and 5 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 929
Sc

1 926
+ Sc
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+ Sc
+ Hs
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+ Hs
+ Sp
+ Sp
+ Sc
+ Sp
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024