HitPredict

Interactor 1: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Interactor 2: NINL (Q9Y2I6)
Ninein-like protein
Gene: NINL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	26638075, 28718761
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 857 Hs			1 1382
+	Hs
		755597 TTK_HUMAN (1-857): 0: 778: 100.00		NIN_HUMAN (693-1358): 6e-17: 89.2: 8.94
+	Hs
		1110596 KCC2D_HUMAN (519-856): 1.1e-113: 357: 22.95		NINL_HUMAN (1-1382): 1.12e-100: 354: 100.00
+	Hs
		1462760 KCC2A_HUMAN (525-856): 3.54e-95: 308: 22.13		NINL_HUMAN (1-1382): 1.12e-100: 354: 100.00
+	Hs
		1143050 KPCD1_HUMAN (175-857): 6.92e-134: 423: 15.61		PLEC_HUMAN (141-1132): 2.84e-25: 117: 10.73
+	Hs
		317396 KPCD3_HUMAN (174-853): 4.51e-131: 415: 15.32		MYH3_HUMAN (797-1375): 1.78e-17: 91.1: 13.11
+	Hs
		587669 KPCD1_HUMAN (175-857): 6.92e-134: 423: 15.61		DESP_HUMAN (382-835): 1.56e-09: 65.2: 15.40
+	Hs
		773003 KPCD2_HUMAN (140-855): 1.38e-118: 382: 14.66		MYH9_HUMAN (37-554): 3.89e-11: 70.3: 9.27
+	Hs
		1110501 KCC2D_HUMAN (519-856): 1.1e-113: 357: 22.95		NIN_HUMAN (693-1358): 6e-17: 89.2: 8.94
+	Hs
		1142010 KS6A6_HUMAN (514-850): 1.43e-93: 312: 21.69		EEA1_HUMAN (21-612): 1.28e-18: 94.6: 11.04
+	Hs
		556878 SNRK_HUMAN (524-792): 7.55e-22: 103: 28.16		MYH1_HUMAN (700-1381): 4.38e-21: 103: 10.87
+	Hs
		1142052 M3K4_HUMAN (530-795): 2.2e-22: 105: 27.47		EEA1_HUMAN (21-612): 1.28e-18: 94.6: 11.04
+	Hs
		1448479 SNRK_HUMAN (524-792): 7.55e-22: 103: 28.16		MYH2_HUMAN (3-569): 4.05e-13: 76.9: 12.37