HitPredict

Interactor 1: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Interactor 2: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.907

The method score is based on:

Property Details
Experiments 12614612, 17296731, 12694531, 31839598, 23764002
Identification Methods two hybrid, affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0003678 - DNA helicase activity
GO:0003697 - single-stranded DNA binding
and 16 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 719
Hs

1 719
+ Hs
+ Xl
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+ Hs
+ Xl
+ Xl
+ Xl
+ Xl
+ Dm
+ Dm
+ Xl
+ Dm
+ Sp
+ Hs
+ At
+ Hs
+ Hs
+ Ce

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Last updated: 11Aug2025