Interactor 1: MCM5 (P33992)
DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46)
Gene: MCM5
Interactor 2: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.962 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9099751, 33961781, 23993743, 12614612, 11248027, 15232106, 33654309, 23764002 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, protein array |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM~MCM5_C, MCM5_C~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB |
| Common GO terms | GO:0000727 - double-strand break repair via break-induced replication GO:0000781 - chromosome, telomeric region GO:0003697 - single-stranded DNA binding GO:0005524 - ATP binding GO:0005634 - nucleus and 8 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
