HitPredict

Interactor 1: UCHL (P35122)
Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (Ubiquitin thioesterase)
Gene: Uch

Interactor 2: PSA6 (Q9XZJ4)
Proteasome subunit alpha type-6 (20S proteasome subunit alpha-1)
Gene: Prosalpha1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 227 Dm			1 244
+	Hs
		681248 UCHL5_HUMAN (4-227): 7.04e-102: 300: 26.09		PSA2_HUMAN (7-241): 4.47e-107: 310: 32.34
+	Hs
		954936 UCHL5_HUMAN (4-227): 7.04e-102: 300: 26.09		PSA6_HUMAN (1-244): 9.97e-104: 302: 66.67
+	Dm
		762516 UCHL_DROME (1-227): 6.24e-100: 291: 100.00		PSA2_DROME (8-240): 1.19e-104: 304: 30.04
+	Hs
		700768 UCHL5_HUMAN (4-227): 7.04e-102: 300: 26.09		PSA5_HUMAN (1-240): 5.31e-97: 285: 28.57
+	Hs
		681207 BAP1_HUMAN (4-227): 1.64e-86: 272: 25.83		PSA2_HUMAN (7-241): 4.47e-107: 310: 32.34
+	Hs
		681750 UCHL5_HUMAN (4-227): 7.04e-102: 300: 26.09		PSA4_HUMAN (6-237): 2.59e-93: 276: 29.11
+	Dm
		762574 UCHL_DROME (1-227): 6.24e-100: 291: 100.00		PSA5_DROME (1-241): 1.44e-96: 283: 27.02
+	Hs
		954869 BAP1_HUMAN (4-227): 1.64e-86: 272: 25.83		PSA6_HUMAN (1-244): 9.97e-104: 302: 66.67
+	Hs
		165444 UCHL5_HUMAN (4-227): 7.04e-102: 300: 26.09		PSA7_HUMAN (9-238): 2.37e-92: 273: 31.03
+	Sp
		314315 UBLH2_SCHPO (2-227): 1.42e-86: 259: 28.45		PSA1_SCHPO (5-244): 3.53e-105: 305: 53.91
+	Hs
		488437 UCHL1_HUMAN (2-225): 4.48e-87: 258: 44.69		PSA6_HUMAN (1-244): 9.97e-104: 302: 66.67
+	Hs
		700698 BAP1_HUMAN (4-227): 1.64e-86: 272: 25.83		PSA5_HUMAN (1-240): 5.31e-97: 285: 28.57
+	Hs
		681693 BAP1_HUMAN (4-227): 1.64e-86: 272: 25.83		PSA4_HUMAN (6-237): 2.59e-93: 276: 29.11
+	Hs
		165387 BAP1_HUMAN (4-227): 1.64e-86: 272: 25.83		PSA7_HUMAN (9-238): 2.37e-92: 273: 31.03
+	Sp
		1462954 UBLH2_SCHPO (2-227): 1.42e-86: 259: 28.45		PSA5_SCHPO (1-243): 7.52e-96: 282: 26.51
+	Hs
		488405 UCHL1_HUMAN (2-225): 4.48e-87: 258: 44.69		PSA4_HUMAN (6-237): 2.59e-93: 276: 29.11
+	Sp
		1068363 UBLH2_SCHPO (2-227): 1.42e-86: 259: 28.45		PSA3_SCHPO (6-242): 1.48e-91: 271: 31.69
+	Dm
		762589 UCHL_DROME (1-227): 6.24e-100: 291: 100.00		PSA3_DROME (8-242): 5.24e-33: 122: 30.51
+	Sp
		1082947 UBLH2_SCHPO (2-227): 1.42e-86: 259: 28.45		PSA4_SCHPO (7-204): 7.48e-35: 126: 34.17
+	Sp
		314466 UBLH2_SCHPO (2-227): 1.42e-86: 259: 28.45		PSA2_SCHPO (13-240): 3.05e-34: 124: 33.75