HitPredict

Interactor 1: UBL1 (P35127)
Ubiquitin carboxyl-terminal hydrolase YUH1 (UCH) (EC 3.4.19.12) (Ubiquitin thioesterase)
Gene: YUH1

Interactor 2: RUB1 (Q03919)
NEDD8-like protein RUB1 (Related to ubiquitin protein 1) (Ubiquitin-like protein RUB1)
Gene: RUB1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12455997
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Peptidase_C12~ubiquitin
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 236 Sc			1 77
+	Dm
		583729 Q9XZ61_DROME (1-234): 3.18e-89: 268: 18.72		RS27A_DROME (1-76): 1.21e-36: 121: 52.63
+	Hs
		987140 BAP1_HUMAN (5-234): 3.55e-78: 250: 18.44		RS27A_HUMAN (1-76): 3.49e-37: 123: 52.63
+	Dm
		583681 CALYP_DROME (1-234): 1.56e-75: 237: 18.33		RS27A_DROME (1-76): 1.21e-36: 121: 52.63
+	Sp
		154031 UBLH2_SCHPO (8-234): 3.96e-81: 246: 22.27		UBL1_SCHPO (1-77): 1.92e-33: 111: 59.74
+	Sc
		509887 UBL1_YEAST (1-236): 2.53e-80: 242: 100.00		RL40A_YEAST (1-76): 8.3e-34: 113: 52.63
+	Hs
		583868 UCHL3_HUMAN (4-232): 1.4e-78: 237: 30.13		NEDD8_HUMAN (1-76): 1.62e-34: 113: 59.21
+	Sc
		436370 UBL1_YEAST (1-236): 2.53e-80: 242: 100.00		RS31_YEAST (1-70): 2.29e-30: 105: 50.00
+	Hs
		507066 UCHL3_HUMAN (4-232): 1.4e-78: 237: 30.13		UBB_HUMAN (1-76): 2.38e-31: 110: 52.63
+	Hs
		583873 UCHL3_HUMAN (4-232): 1.4e-78: 237: 30.13		Q5U5U6_HUMAN (1-76): 2.38e-31: 110: 52.63
+	Hs
		488443 UCHL1_HUMAN (10-233): 5.59e-73: 223: 25.43		RS27A_HUMAN (1-76): 3.49e-37: 123: 52.63
+	Hs
		488482 UCHL1_HUMAN (10-233): 5.59e-73: 223: 25.43		NEDD8_HUMAN (1-76): 1.62e-34: 113: 59.21
+	Hs
		488379 UCHL1_HUMAN (10-233): 5.59e-73: 223: 25.43		UBB_HUMAN (1-76): 2.38e-31: 110: 52.63
+	Sc
		509486 UBL1_YEAST (1-236): 2.53e-80: 242: 100.00		UBI4P_YEAST (1-76): 1.14e-16: 73.9: 52.63
+	Sp
		154028 UBLH1_SCHPO (8-231): 8.27e-55: 176: 24.03		UBL1_SCHPO (1-77): 1.92e-33: 111: 59.74