HitPredict

Interactor 1: SPT7 (P35177)
SAGA complex subunit SPT7 (Suppressor of Ty protein 7) (Transcriptional activator SPT7)
Gene: SPT7

Interactor 2: CENPA (P36012)
Histone H3-like centromeric protein CSE4 (CENP-A homolog) (CENPA homolog) (Chromosome segregation protein 4)
Gene: CSE4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21070971
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1332 Sc			1 229
+	Sc
		763001 SPT7_YEAST (1-1332): 0: 1180: 100.00		H3_YEAST (93-227): 1.72e-43: 144: 47.45
+	Hs
		998491 PB1_HUMAN (256-1099): 3.26e-134: 453: 13.17		H31_HUMAN (93-227): 5.03e-52: 166: 51.10
+	Hs
		1161923 PB1_HUMAN (256-1099): 3.26e-134: 453: 13.17		H31T_HUMAN (93-227): 7.09e-51: 163: 48.91
+	Hs
		1016988 PB1_HUMAN (256-1099): 3.26e-134: 453: 13.17		H33_HUMAN (93-227): 1.39e-50: 162: 51.83
+	Hs
		883596 PB1_HUMAN (256-1099): 3.26e-134: 453: 13.17		CENPA_HUMAN (139-226): 6.59e-22: 89.4: 57.96
+	Hs
		998921 BAZ2A_HUMAN (149-547): 1.19e-75: 279: 15.33		H31_HUMAN (93-227): 5.03e-52: 166: 51.10
+	Hs
		1017280 BAZ2A_HUMAN (149-547): 1.19e-75: 279: 15.33		H33_HUMAN (93-227): 1.39e-50: 162: 51.83
+	Hs
		998599 PHIP_HUMAN (256-918): 9.46e-74: 273: 11.66		H31_HUMAN (93-227): 5.03e-52: 166: 51.10
+	Hs
		1017060 PHIP_HUMAN (256-918): 9.46e-74: 273: 11.66		H33_HUMAN (93-227): 1.39e-50: 162: 51.83
+	Hs
		1258891 PHIP_HUMAN (256-918): 9.46e-74: 273: 11.66		H32_HUMAN (93-227): 2.04e-50: 162: 51.83
+	Hs
		998920 BAZ2B_HUMAN (134-547): 2.6e-69: 259: 18.75		H31_HUMAN (93-227): 5.03e-52: 166: 51.10
+	Dm
		381744 NU301_DROME (117-553): 1.51e-67: 254: 13.51		H3_DROME (93-227): 2.04e-50: 162: 51.83
+	Hs
		903125 SMCA2_HUMAN (179-630): 1.41e-63: 240: 10.60		H31_HUMAN (93-227): 5.03e-52: 166: 51.10
+	Hs
		903310 SMCA4_HUMAN (179-590): 4.82e-63: 239: 10.35		H31_HUMAN (93-227): 5.03e-52: 166: 51.10
+	Hs
		903382 SMCA4_HUMAN (179-590): 4.82e-63: 239: 10.35		H31T_HUMAN (93-227): 7.09e-51: 163: 48.91
+	Hs
		903314 SMCA4_HUMAN (179-590): 4.82e-63: 239: 10.35		H33_HUMAN (93-227): 1.39e-50: 162: 51.83
+	Hs
		903400 SMCA4_HUMAN (179-590): 4.82e-63: 239: 10.35		H32_HUMAN (93-227): 2.04e-50: 162: 51.83
+	Hs
		883726 BAZ2A_HUMAN (149-547): 1.19e-75: 279: 15.33		CENPA_HUMAN (139-226): 6.59e-22: 89.4: 57.96
+	Hs
		883631 PHIP_HUMAN (256-918): 9.46e-74: 273: 11.66		CENPA_HUMAN (139-226): 6.59e-22: 89.4: 57.96
+	Hs
		883486 SMCA2_HUMAN (179-630): 1.41e-63: 240: 10.60		CENPA_HUMAN (139-226): 6.59e-22: 89.4: 57.96