HitPredict

Interactor 1: SMCA4 (P51532)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 (SMARCA4) (EC 3.6.4.-) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (Transcription activator BRG1)
Gene: SMARCA4

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	17274598
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~SnAC, Histone~SNF2-rel_dom
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1647 Hs			1 136
+	Hs
		903310 SMCA4_HUMAN (1-1647): 0: 1088: 100.00		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		903314 SMCA4_HUMAN (1-1647): 0: 1088: 100.00		H33_HUMAN (1-136): 2.57e-61: 186: 97.06
+	Hs
		903382 SMCA4_HUMAN (1-1647): 0: 1088: 100.00		H31T_HUMAN (1-136): 1.38e-61: 186: 96.32
+	Hs
		903125 SMCA2_HUMAN (40-1647): 0: 958: 72.59		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		883486 SMCA2_HUMAN (40-1647): 0: 958: 72.59		CENPA_HUMAN (9-133): 2.87e-44: 143: 50.00
+	Dm
		381692 BRM_DROME (211-1643): 0: 844: 53.24		H3_DROME (1-136): 6.24e-61: 185: 100.00
+	Hs
		703289 SMCA1_HUMAN (639-1621): 0: 830: 29.20		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		703293 SMCA1_HUMAN (639-1621): 0: 830: 29.20		H33_HUMAN (1-136): 2.57e-61: 186: 97.06
+	Hs
		243594 SMCA5_HUMAN (594-1622): 0: 815: 27.27		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Hs
		243599 SMCA5_HUMAN (594-1622): 0: 815: 27.27		H33_HUMAN (1-136): 2.57e-61: 186: 97.06
+	Mm
		999034 SMCA5_MOUSE (599-1622): 0: 812: 27.12		H31_MOUSE (1-136): 3.1e-62: 188: 99.27
+	Mm
		1017370 SMCA5_MOUSE (599-1622): 0: 812: 27.12		H33_MOUSE (1-136): 2.57e-61: 186: 97.06
+	Mm
		1016767 SMCA5_MOUSE (599-1622): 0: 812: 27.12		H32_MOUSE (1-136): 6.24e-61: 185: 100.00
+	Sp
		489143 SNF21_SCHPO (461-1587): 0: 799: 39.12		H31_SCHPO (1-136): 3.44e-59: 181: 91.91
+	Hs
		703282 SMCA1_HUMAN (639-1621): 0: 830: 29.20		CENPA_HUMAN (9-133): 2.87e-44: 143: 50.00
+	Hs
		243575 SMCA5_HUMAN (594-1622): 0: 815: 27.27		CENPA_HUMAN (9-133): 2.87e-44: 143: 50.00
+	Mm
		59101 CHD5_MOUSE (739-1497): 0: 744: 32.23		H33_MOUSE (1-136): 2.57e-61: 186: 97.06
+	Sc
		743121 STH1_YEAST (539-1563): 0: 740: 36.33		H3_YEAST (1-136): 1.23e-55: 171: 88.97
+	Sc
		963771 ISW2_YEAST (576-1629): 0: 739: 25.47		H3_YEAST (1-136): 1.23e-55: 171: 88.97
+	Sc
		743079 STH1_YEAST (539-1563): 0: 740: 36.33		CENPA_YEAST (18-134): 2.58e-43: 143: 56.67