HitPredict

Interactor 1: NOS2 (P35228)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Interactor 2: SPSB1 (Q96BD6)
SPRY domain-containing SOCS box protein 1 (SSB-1)
Gene: SPSB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	21199876, 21549100, 20603330, 23438482
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1153 Hs			1 273
+	Hs
		766215 NOS2_HUMAN (1-1153): 0: 1802: 100.00		SPSB4_HUMAN (1-273): 1.02e-119: 345: 74.73
+	Hs
		766222 NOS2_HUMAN (1-1153): 0: 1802: 100.00		SPSB2_HUMAN (1-273): 3.24e-94: 280: 50.18
+	Hs
		504712 NOS2_HUMAN (1-1153): 0: 1802: 100.00		FBSP1_HUMAN (22-230): 1.1e-69: 218: 36.02
+	Hs
		766206 NOS2_HUMAN (1-1153): 0: 1802: 100.00		HERC1_HUMAN (22-225): 8.37e-39: 146: 20.38
+	Hs
		766211 NOS2_HUMAN (1-1153): 0: 1802: 100.00		TRI67_HUMAN (52-232): 7.62e-36: 137: 17.11
+	Hs
		596667 NCPR_HUMAN (502-1128): 0: 750: 29.78		TRI67_HUMAN (52-232): 7.62e-36: 137: 17.11
+	Hs
		1255971 NDOR1_HUMAN (536-1129): 0: 581: 26.71		TRI67_HUMAN (52-232): 7.62e-36: 137: 17.11