HitPredict

Interactor 1: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Interactor 2: PPT1 (P53043)
Serine/threonine-protein phosphatase T (PPT) (EC 3.1.3.16)
Gene: PPT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	23332755, 19536198
Identification Methods	biochemical, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 613 Sc			1 513
+	Sc
		512026 SSB1_YEAST (1-613): 0: 1118: 99.35		PPT1_YEAST (1-513): 4.91e-168: 486: 100.00
+	Sc
		696340 SSB2_YEAST (1-613): 0: 1122: 100.00		PP12_YEAST (189-492): 1.5e-156: 449: 34.10
+	Sc
		510663 SSB1_YEAST (1-613): 0: 1118: 99.35		PP12_YEAST (189-492): 1.5e-156: 449: 34.10
+	Hs
		564043 HSP76_HUMAN (3-612): 0: 898: 58.82		PPP5_HUMAN (2-513): 0: 521: 37.70
+	Hs
		503738 HSP7C_HUMAN (5-612): 0: 897: 60.00		PPP5_HUMAN (2-513): 0: 521: 37.70
+	Mm
		926131 HSP7C_MOUSE (5-612): 0: 896: 60.00		PPP5_MOUSE (2-513): 2.39e-180: 517: 38.09
+	Hs
		503821 HSP7C_HUMAN (5-612): 0: 897: 60.00		PP1A_HUMAN (191-508): 3.85e-162: 464: 31.79
+	Hs
		503837 HSP7C_HUMAN (5-612): 0: 897: 60.00		PP2AB_HUMAN (188-498): 2.36e-161: 461: 33.01
+	Mm
		571850 HS71B_MOUSE (5-611): 0: 889: 59.61		PP1B_MOUSE (191-507): 1.52e-163: 468: 31.88
+	Hs
		713936 HS71L_HUMAN (5-612): 0: 893: 59.51		PP1A_HUMAN (191-508): 3.85e-162: 464: 31.79
+	Hs
		905943 Q53FA3_HUMAN (5-612): 0: 893: 59.67		PP1A_HUMAN (191-508): 3.85e-162: 464: 31.79
+	Hs
		503566 HSP7C_HUMAN (5-612): 0: 897: 60.00		PP1G_HUMAN (191-505): 2.13e-160: 459: 32.28
+	Hs
		503863 HSP7C_HUMAN (5-612): 0: 897: 60.00		PP2AA_HUMAN (195-498): 1.67e-160: 459: 32.79
+	Mm
		571849 HS71B_MOUSE (5-611): 0: 889: 59.61		PP1A_MOUSE (191-508): 2.43e-162: 464: 31.79
+	Hs
		713915 HS71L_HUMAN (5-612): 0: 893: 59.51		PP1G_HUMAN (191-505): 2.13e-160: 459: 32.28
+	Mm
		571852 HS71B_MOUSE (5-611): 0: 889: 59.61		PP1G_MOUSE (191-505): 1.52e-160: 460: 32.28
+	Hs
		737670 HSP72_HUMAN (4-612): 0: 888: 60.13		PP1G_HUMAN (191-505): 2.13e-160: 459: 32.28
+	Sc
		688122 SSB2_YEAST (1-613): 0: 1122: 100.00		PP4C_YEAST (206-497): 3.23e-59: 199: 37.54
+	Sc
		510576 SSB1_YEAST (1-613): 0: 1118: 99.35		PP4C_YEAST (206-497): 3.23e-59: 199: 37.54
+	Sc
		449953 HSP73_YEAST (9-611): 0: 677: 60.66		PP4C_YEAST (206-497): 3.23e-59: 199: 37.54