Protein: DEDD2
DNA-binding death effector domain-containing protein 2 (DED-containing protein FLAME-3) (FADD-like anti-apoptotic molecule 3)

Gene: DEDD2
Organism: Homo sapiens
Interactions: 18
UniProt ID: Q8WXF8

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006396 - RNA processing
GO:0008625 - extrinsic apoptotic signaling pathway via death domain receptors

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

271706

DEDD
Death effector domain-containing protein

2

2

Small-scale

0.843

High

1059331

CASP8
Caspase-8

2

5

Small-scale

0.819

High

1263647

DEDD2
DNA-binding death effector domain-containing protein 2

2

2

Small-scale

0.789

High

181627

CFLAR
CASP8 and FADD-like apoptosis regulator

2

5

Small-scale

0.746

High

960221

CDK6
Cyclin-dependent kinase 6

1

1

Small-scale

0.735

High

1263648

CASPA
Caspase-10

1

5

Small-scale

0.665

High

1263652

TF3C3
General transcription factor 3C polypeptide 3

1

2

Small-scale

0.561

High

1161812

FBX38
F-box only protein 38

2

1

Small-scale

0.533

High

198943

RFOX2
RNA binding protein fox-1 homolog 2

1

0

High-throughput

0.518

High

1263650

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

0

High-throughput

0.518

High

1263653

NR2E3
Photoreceptor-specific nuclear receptor

1

0

High-throughput

0.518

High

1263649

CDA7L
Cell division cycle-associated 7-like protein

1

0

High-throughput

0.460

High

989034

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.438

High

779814

CCNF
Cyclin-F

1

2

High-throughput

0.437

High

1146670

A16L1
Autophagy-related protein 16-1

2

0

Small-scale

0.319

High

1263651

RHXF2
Rhox homeobox family member 2

1

0

High-throughput

0.282

High

1146135

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024