Protein: 5HT2B
5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)

Gene: 5HT2B, HTR2B
Organism: Homo sapiens
Interactions: 32
UniProt ID: P41595

Gene Ontology (top 5):
GO:0001587 - Gq/11-coupled serotonin receptor activity
GO:0001755 - neural crest cell migration
GO:0001819 - positive regulation of cytokine production
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0001965 - G-protein alpha-subunit binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

835452

RAE1L
mRNA export factor RAE1

1

0

High-throughput

0.663

High

701446

5HT2A
5-hydroxytryptamine receptor 2A

1

15

Small-scale

0.618

High

702748

5HT2C
5-hydroxytryptamine receptor 2C

1

15

Small-scale

0.618

High

720649

AGTR1
Type-1 angiotensin II receptor

1

19

Small-scale

0.618

High

168203

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.541

High

239356

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

1

High-throughput

0.541

High

420775

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.541

High

835453

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

1

High-throughput

0.541

High

835457

HDGR2
Hepatoma-derived growth factor-related protein 2

1

1

High-throughput

0.541

High

835460

NIPA2
Magnesium transporter NIPA2

1

1

High-throughput

0.541

High

835466

ABCA3
Phospholipid-transporting ATPase ABCA3

1

4

High-throughput

0.541

High

835454

SNTA1
Alpha-1-syntrophin

1

20

Small-scale

0.527

High

835462

LNX1
E3 ubiquitin-protein ligase LNX

1

20

Small-scale

0.527

High

190547

COPT2
Protein SLC31A2

1

0

High-throughput

0.518

High

835450

OAZ1
Ornithine decarboxylase antizyme 1

1

0

High-throughput

0.518

High

835455

KIF19
Kinesin-like protein KIF19

1

0

High-throughput

0.518

High

835458

CTL2
Choline transporter-like protein 2

1

0

High-throughput

0.518

High

835469

PLLP
Plasmolipin

1

0

High-throughput

0.518

High

405255

OAT
Ornithine aminotransferase, mitochondrial

1

1

High-throughput

0.515

High

299746

MPDZ
Multiple PDZ domain protein

1

20

Small-scale

0.501

High

592813

CBR1
Carbonyl reductase [NADPH] 1

1

1

High-throughput

0.494

High

835449

MATR3
Matrin-3

1

1

High-throughput

0.494

High

835451

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

1

High-throughput

0.494

High

835459

TR1L1
Translocating chain-associated membrane protein 1-like 1

1

9

High-throughput

0.494

High

835464

NAT14
Probable N-acetyltransferase 14

1

1

High-throughput

0.494

High

835465

WRIP1
ATPase WRNIP1

1

1

Small-scale

0.437

High

192461

INSI1
Insulin-induced gene 1 protein

1

0

High-throughput

0.282

High

835456

PPR3F
Protein phosphatase 1 regulatory subunit 3F

1

0

High-throughput

0.282

High

835463

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.282

High

835467

G6PC3
Glucose-6-phosphatase 3

1

0

High-throughput

0.282

High

835468

METRN
Meteorin

1

0

High-throughput

0.282

High

835461

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025