Interactor 1: PPM1A (P35813)
Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA)
Gene: PPM1A
Interactor 2: MP2K6 (P52564)
Dual specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase 6) (MAPKK 6) (EC 2.7.12.2) (MAPK/ERK kinase 6) (MEK 6) (Stress-activated protein kinase kinase 3) (SAPK kinase 3) (SAPKK-3) (SAPKK3)
Gene: MAP2K6
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9707433 |
| Identification Methods | phosphatase assay |
| Interaction Type | dephosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PP2C~Pkinase |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0051726 - regulation of cell cycle |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
