Protein: PP2C1
Protein phosphatase 2C homolog 1 (PP2C-1) (EC 3.1.3.16)

Gene: PP2C1, PTC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P35182

Gene Ontology (top 5):
GO:0000001 - mitochondrion inheritance
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

464584

PBS2
MAP kinase kinase PBS2

4

12

Small-scale

0.894

High

763242

SKM1
Serine/threonine-protein kinase SKM1

2

9

High-throughput

0.811

High

763234

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

2

12

High-throughput

0.793

High

763229

CLA4
Serine/threonine-protein kinase CLA4

2

13

High-throughput

0.767

High

763240

NBP2
NAP1-binding protein 2

8

1

Small-scale

0.751

High

574664

KSS1
Mitogen-activated protein kinase KSS1

1

14

High-throughput

0.724

High

602397

PHO85
Cyclin-dependent protein kinase PHO85

1

3

High-throughput

0.647

High

642361

MCK1
Protein kinase MCK1

1

8

High-throughput

0.647

High

656740

KC12
Casein kinase I homolog 2

1

6

High-throughput

0.647

High

671948

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

20

High-throughput

0.647

High

672186

KIN82
Serine/threonine-protein kinase KIN82

1

3

High-throughput

0.647

High

692329

KCC1
Calcium/calmodulin-dependent protein kinase I

1

8

High-throughput

0.647

High

735479

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

9

High-throughput

0.647

High

737822

HOG1
Mitogen-activated protein kinase HOG1

1

13

Small-scale

0.647

High

738022

MKK1
MAP kinase kinase MKK1/SSP32

1

12

Small-scale

0.647

High

739946

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

14

High-throughput

0.647

High

740564

IME2
Meiosis induction protein kinase IME2/SME1

1

12

High-throughput

0.647

High

763221

KKQ8
Probable serine/threonine-protein kinase KKQ8

1

20

High-throughput

0.647

High

763224

RCK1
Serine/threonine-protein kinase RCK1

1

14

High-throughput

0.647

High

763235

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

20

High-throughput

0.647

High

673696

KCC4
Probable serine/threonine-protein kinase KCC4

1

20

High-throughput

0.621

High

758287

HSL1
Probable serine/threonine-protein kinase HSL1

1

20

High-throughput

0.621

High

763220

PP2C1
Protein phosphatase 2C homolog 1

1

3

High-throughput

0.621

High

763236

STE20
Serine/threonine-protein kinase STE20

1

9

High-throughput

0.621

High

763241

GIN4
Serine/threonine-protein kinase GIN4

1

20

High-throughput

0.621

High

763230

FMP48
Probable serine/threonine-protein kinase FMP48

1

16

High-throughput

0.579

High

763239

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

2

0

High-throughput

0.563

High

721831

XPO1
Exportin-1

1

1

High-throughput

0.536

High

763223

TSL1
Trehalose synthase complex regulatory subunit TSL1

1

0

High-throughput

0.513

High

763238

CDC53
Cell division control protein 53

1

0

High-throughput

0.513

High

763231

ARE2
Sterol O-acyltransferase 2

1

2

High-throughput

0.489

High

763222

FAT2
Oxalate--CoA ligase

1

0

High-throughput

0.486

High

647744

RFA1
Replication factor A protein 1

1

3

Small-scale

0.481

High

670246

NAP1
Nucleosome assembly protein

1

1

High-throughput

0.481

High

748616

STE5
Protein STE5

1

0

Small-scale

0.480

High

763232

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

763225

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

High-throughput

0.460

High

706725

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

763233

CDC14
Tyrosine-protein phosphatase CDC14

1

0

Small-scale

0.458

High

763226

MET30
F-box protein MET30

1

1

High-throughput

0.457

High

763228

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

672640

BPH1
Beige protein homolog 1

1

1

High-throughput

0.437

High

698099

PEP3
Vacuolar membrane protein PEP3

1

0

High-throughput

0.279

Low

366994

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.261

Low

763227

FIR1
Factor interacting with REF2

1

0

Small-scale

0.251

Low

763237

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025