HitPredict

Interactor 1: PARP (P35875)
Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase) (ADPRT) (Poly[ADP-ribose] synthase) (Protein ADP-ribosyltransferase Parp) (EC 2.4.2.-)
Gene: PARP

Interactor 2: PARP (P35875)
Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase) (ADPRT) (Poly[ADP-ribose] synthase) (Protein ADP-ribosyltransferase Parp) (EC 2.4.2.-)
Gene: PARP

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17827147
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT~BRCT, PADR1_N~PADR1_N, PADR1_N~zf-PARP, PADR1_N~PADR1_Zn_ribbon, PARP~PARP, PARP~PARP_reg, PARP_reg~PARP_reg, PARP_reg~WGR, PADR1_Zn_ribbon~PARP_reg, WGR~zf-PARP, PADR1_Zn_ribbon~WGR, zf-PARP~zf-PARP, PADR1_Zn_ribbon~zf-PARP
Common GO terms GO:0000791 - euchromatin
GO:0003677 - DNA binding
GO:0003950 - NAD+ poly-ADP-ribosyltransferase activity
GO:0005694 - chromosome
GO:0005730 - nucleolus
and 28 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 994
Dm

1 994
+ At
+ At
+ At
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
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+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 11Aug2025