HitPredict

Interactor 1: VGFR2 (P35918)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase NYK) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: Kdr

Interactor 2: DAB2 (P98078)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)
Gene: DAB2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	23354168
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1345 Mm			1 766
+	Mm
		777817 VGFR3_MOUSE (24-1340): 0: 816: 41.81		DAB2_MOUSE (1-766): 2.91e-93: 309: 100.00
+	Mm
		483862 CSF1R_MOUSE (1-323): 7.2e-23: 108: 10.26		DAB2_MOUSE (1-766): 2.91e-93: 309: 100.00
+	Hs
		648480 FGFR4_HUMAN (1-225): 6.66e-27: 120: 11.72		DAB2_HUMAN (1-766): 9.44e-78: 267: 81.63
+	Hs
		532088 KIT_HUMAN (15-543): 3.41e-47: 186: 16.79		SHC4_HUMAN (2-337): 1.59e-42: 166: 12.37
+	Hs
		648460 FGFR4_HUMAN (1-225): 6.66e-27: 120: 11.72		NUMB_HUMAN (20-678): 7.45e-47: 179: 14.79
+	Hs
		593531 PGFRA_HUMAN (1-415): 2.63e-27: 122: 13.16		DP13A_HUMAN (20-246): 6.78e-36: 146: 12.66
+	Hs
		648727 FGFR4_HUMAN (1-225): 6.66e-27: 120: 11.72		DP13A_HUMAN (20-246): 6.78e-36: 146: 12.66
+	Hs
		648612 FGFR4_HUMAN (1-225): 6.66e-27: 120: 11.72		ANS1A_HUMAN (1-248): 1.52e-34: 144: 19.44
+	Hs
		648759 FGFR4_HUMAN (1-225): 6.66e-27: 120: 11.72		NUMBL_HUMAN (11-539): 3.91e-35: 143: 14.55
+	Hs
		541751 FGFR1_HUMAN (1-154): 2.4e-15: 83.5: 12.57		DP13A_HUMAN (20-246): 6.78e-36: 146: 12.66
+	Hs
		541790 FGFR1_HUMAN (1-154): 2.4e-15: 83.5: 12.57		NUMBL_HUMAN (11-539): 3.91e-35: 143: 14.55