Interactor 1: CSK (P41241)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase MPK-2) (p50CSK)
Gene: CSK
Interactor 2: PK3CA (P42337)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)
Gene: Pik3ca
Species: Mus musculus
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.41 | 1.00 | 0.646 |
The method score is based on:
Property | Details |
---|---|
Experiments | 27474268 |
Identification Methods | anti bait coimmunoprecipitation |
Interaction Type | association, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PI3_PI4_kinase~SH2, PI3K_C2~SH2, PI3Ka~SH2 |
Common GO terms | GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane |
Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024