Interactor 1: STAT3 (P42227)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: Q99K94 (Q99K94)
Signal transducer and activator of transcription
Gene: Stat1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 20211142
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, STAT_alpha~STAT_bind, STAT_alpha~STAT_int, STAT_bind~STAT_bind, STAT_int~STAT_int
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 770
Mm

1 712
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Last updated: 15 Jul 2024