Interactor 1: MTHR (P42898)
Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53)
Gene: MTHFR

Interactor 2: MTHR (P42898)
Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53)
Gene: MTHFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19610625
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MTHFR~MTHFR
Common GO terms GO:0001666 - response to hypoxia
GO:0001843 - neural tube closure
GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0005829 - cytosol
GO:0006555 - methionine metabolic process
and 16 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 656
Hs

1 656
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024