HitPredict

Interactor 1: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Hs			1 232
+	Hs
		793253 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		793248 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		793241 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		793262 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		793246 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		793257 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		545250 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		793252 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		793271 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		436192 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		793258 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120335 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		793479 MUC18_HUMAN (1-646): 3.41e-136: 414: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Hs
		892359 CD166_HUMAN (13-607): 2.71e-98: 314: 22.33		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		915989 ROBO2_HUMAN (1-646): 1.16e-96: 325: 14.69		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		915663 CD166_HUMAN (13-607): 2.71e-98: 314: 22.33		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		894276 PXDN_HUMAN (183-555): 5.6e-61: 222: 20.77		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		530163 NCAM1_HUMAN (11-644): 1.38e-81: 277: 15.63		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		436458 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		120585 KIRR1_HUMAN (240-644): 1.88e-28: 123: 15.77		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76