Interactor 1: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM
Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.980 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10608806, 18571408, 30089259, 28508083, 20026654, 19431188, 18256278, 16540636, 15313175, 20360068, 16858402, 15790808 |
| Identification Methods | unspecified method, enzymatic study, pull down, x-ray crystallography, affinity chromatography technology, biochemical, in-gel kinase assay, tandem affinity purification |
| Interaction Type | direct interaction, association, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FAT~FAT, FAT~FATC, FAT~PI3_PI4_kinase, FATC~PI3_PI4_kinase, PI3_PI4_kinase~PI3_PI4_kinase |
| Common GO terms | GO:0000077 - DNA damage checkpoint signaling GO:0000425 - pexophagy GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0000729 - DNA double-strand break processing and 83 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025