HitPredict

Interactor 1: GATA4 (P43694)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Interactor 2: SMRC1 (Q92922)
SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1)
Gene: SMARCC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35182466
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 442 Hs			1 1105
+	Hs
		620400 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		SMRC1_HUMAN (30-1074): 0: 1148: 100.00
+	Hs
		554494 GATA1_HUMAN (90-422): 4.68e-40: 150: 35.44		SMRC1_HUMAN (30-1074): 0: 1148: 100.00
+	Hs
		620546 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		SMRC1_HUMAN (30-1074): 0: 1148: 100.00
+	Hs
		798951 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		SMRC2_HUMAN (32-1105): 0: 956: 57.71
+	Hs
		620389 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		SMRC2_HUMAN (32-1105): 0: 956: 57.71
+	Hs
		554483 GATA1_HUMAN (90-422): 4.68e-40: 150: 35.44		SMRC2_HUMAN (32-1105): 0: 956: 57.71
+	Hs
		799053 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22
+	Hs
		261432 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55
+	Hs
		798872 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		620449 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22
+	Hs
		554535 GATA1_HUMAN (90-422): 4.68e-40: 150: 35.44		NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22
+	Hs
		620599 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22
+	Hs
		261404 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55
+	Hs
		998949 GATA6_HUMAN (1-433): 2.4e-44: 165: 43.84		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		620338 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		554440 GATA1_HUMAN (90-422): 4.68e-40: 150: 35.44		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		261405 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55
+	Hs
		620490 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		620385 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		KMT2C_HUMAN (664-1105): 1.43e-09: 65: 7.64
+	Mm
		1351630 PCLO_MOUSE (11-396): 1.52e-20: 97.3: 11.88		PCLO_MOUSE (679-1105): 8.27e-10: 65.8: 7.66