HitPredict

Interactor 1: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Interactor 2: LAR4B (Q92615)
La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5)
Gene: LARP4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 262 Hs			1 738
+	Hs
		1263443 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		LAR4B_HUMAN (1-738): 0: 654: 100.00
+	Hs
		1031407 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		LAR4B_HUMAN (1-738): 0: 654: 100.00
+	Hs
		952008 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		LARP4_HUMAN (50-738): 1.65e-168: 503: 36.78
+	Hs
		1116414 SRS12_HUMAN (1-251): 1.31e-38: 137: 46.33		LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43
+	Hs
		952004 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		LARP1_HUMAN (31-367): 7.91e-52: 197: 16.19
+	Hs
		403370 PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46		LA_HUMAN (156-519): 9.57e-49: 179: 10.15
+	Hs
		1031367 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		LARP1_HUMAN (31-367): 7.91e-52: 197: 16.19
+	Hs
		516561 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		LARP1_HUMAN (31-367): 7.91e-52: 197: 16.19
+	Hs
		403212 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		LA_HUMAN (156-519): 9.57e-49: 179: 10.15
+	Hs
		951983 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43
+	Hs
		963998 SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65		LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43
+	Mm
		985649 SRSF2_MOUSE (4-90): 1.89e-24: 99.3: 45.65		LARP7_MOUSE (129-303): 6.73e-44: 169: 19.90
+	Hs
		1031352 PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37		LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43
+	Hs
		516541 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		LARP7_HUMAN (154-461): 2.7e-44: 170: 15.43
+	Sc
		376709 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		LHP1_YEAST (137-369): 5.71e-44: 161: 17.65
+	Zm
		9088 B4F8E1_MAIZE (5-181): 1.38e-33: 122: 36.16		A0A1D6EU55_MAIZE (100-240): 6.6e-31: 129: 18.88
+	Hs
		951997 SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79		LAR1B_HUMAN (114-266): 3.23e-28: 123: 16.99
+	Dm
		597071 PABP_DROME (2-99): 4.79e-20: 91: 15.31		LARP_DROME (62-250): 4.89e-30: 129: 21.16
+	Hs
		516553 PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35		LAR1B_HUMAN (114-266): 3.23e-28: 123: 16.99
+	Sc
		376650 PABP_YEAST (2-98): 4.25e-20: 91: 24.74		SRO9_YEAST (158-216): 8.85e-09: 60.3: 27.87