HitPredict

Interactor 1: GATA4 (P43694)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	35659652, 35182466
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 504
+	Rn
		803064 GATA4_RAT (1-442): 4.2e-75: 243: 90.07		PRP19_RAT (1-504): 1.79e-165: 479: 99.41
+	Hs
		799000 GATA4_HUMAN (1-442): 5.21e-80: 256: 100.00		TBL1R_HUMAN (134-466): 1.2e-76: 251: 14.57
+	Hs
		620419 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		TBL1R_HUMAN (134-466): 1.2e-76: 251: 14.57
+	Mm
		140193 GATA2_MOUSE (54-403): 6.02e-45: 164: 38.38		FBXW7_MOUSE (88-458): 9.24e-74: 248: 18.06
+	Hs
		620404 GATA2_HUMAN (54-403): 4.51e-44: 162: 38.66		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		620569 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		TBL1R_HUMAN (134-466): 1.2e-76: 251: 14.57
+	Hs
		620550 GATA3_HUMAN (43-387): 3.5e-35: 137: 35.17		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Sp
		999839 FEP1_SCHPO (122-416): 3.41e-16: 82.7: 19.08		TUP11_SCHPO (70-340): 1.86e-44: 167: 13.78