Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 10464310, 8631823, 12615911, 27669437, 31980649, 11369773, 9920935, 10085298, 9581808, 10753828, 15700267, 15673687, 17038317, 19380743, 11839772, 11278916, 15492270, 14657239, 10329689, 16267043 and 5 others

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Identification Methods affinity chromatography technology, pull down, unspecified method, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH3_1, SH3_1~SH3_1, SH3_1~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0015629 - actin cytoskeleton
GO:0016477 - cell migration
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 304
Hs

1 870
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024