HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: Q6NSK7 (Q6NSK7)
RIN3 protein
Gene: RIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 304 Hs			1 908
+	Hs
		802857 CRKL_HUMAN (2-302): 4.5e-57: 187: 48.07		Q6NSK7_HUMAN (1-908): 0: 678: 100.00
+	Hs
		3100 A0A0S2Z3Q4_HUMAN (1-304): 7.82e-68: 215: 100.00		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		802669 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		802875 CRKL_HUMAN (2-302): 4.5e-57: 187: 48.07		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		1167810 DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		1155937 ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86		Q6NSK7_HUMAN (1-908): 0: 678: 100.00
+	Hs
		275213 GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		1117726 Q4LE43_HUMAN (1-302): 9.64e-27: 112: 15.39		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		581028 PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		69536 B0LPF3_HUMAN (135-297): 2.78e-25: 102: 15.67		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		924717 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		1251932 ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		1251962 CD2AP_HUMAN (1-196): 4.74e-12: 68.3: 17.12		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		70370 B2R6S4_HUMAN (2-100): 1.41e-10: 63.3: 18.00		RIN3_HUMAN (1-908): 0: 597: 89.04
+	Hs
		855796 VAV2_HUMAN (2-191): 3.44e-29: 119: 19.74		GAPD1_HUMAN (155-765): 1.05e-73: 267: 15.97
+	Hs
		802854 CRKL_HUMAN (2-302): 4.5e-57: 187: 48.07		TENS2_HUMAN (3-217): 4.89e-32: 137: 19.33
+	Hs
		924632 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		TENS2_HUMAN (3-217): 4.89e-32: 137: 19.33
+	Ce
		110116 Q9U2T9_CAEEL (182-300): 9.9e-11: 64.7: 13.22		TENSH_CAEEL (55-196): 2.35e-27: 122: 17.88
+	Hs
		203218 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		SYNJ1_HUMAN (103-493): 8.16e-10: 65.2: 14.14
+	Ce
		136804 VAV_CAEEL (13-194): 4.87e-22: 98.4: 23.94		UNC89_CAEEL (6-370): 8.13e-10: 65.2: 11.29